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一项关于中澳日养老院疼痛药物管理的混合方法研究。

A mixed-methods study on the pharmacological management of pain in Australian and Japanese nursing homes.

机构信息

Centre for Medicine Use and Safety (CMUS), Faculty of Pharmacy and Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia.

Research Department, Institute for Health Economics and Policy, Association for Health Economics Research and Social Insurance and Welfare, Tokyo, Japan.

出版信息

Age Ageing. 2024 Feb 1;53(2). doi: 10.1093/ageing/afae024.

Abstract

BACKGROUND

Understanding how analgesics are used in different countries can inform initiatives to improve the pharmacological management of pain in nursing homes.

AIMS

To compare patterns of analgesic use among Australian and Japanese nursing home residents; and explore Australian and Japanese healthcare professionals' perspectives on analgesic use.

METHODS

Part one involved a cross-sectional comparison among residents from 12 nursing homes in South Australia (N = 550) in 2019 and four nursing homes in Tokyo (N = 333) in 2020. Part two involved three focus groups with Australian and Japanese healthcare professionals (N = 16) in 2023. Qualitative data were deductively content analysed using the World Health Organization six-step Guide to Good Prescribing.

RESULTS

Australian and Japanese residents were similar in age (median: 89 vs 87) and sex (female: 73% vs 73%). Overall, 74% of Australian and 11% of Japanese residents used regular oral acetaminophen, non-steroidal anti-inflammatory drugs or opioids. Australian and Japanese healthcare professionals described individualising pain management and the first-line use of acetaminophen. Australian participants described their therapeutic goal was to alleviate pain and reported analgesics were often prescribed on a regular basis. Japanese participants described their therapeutic goal was to minimise impacts of pain on daily activities and reported analgesics were often prescribed for short-term durations, corresponding to episodes of pain. Japanese participants described regulations that limit opioid use for non-cancer pain in nursing homes.

CONCLUSION

Analgesic use is more prevalent in Australian than Japanese nursing homes. Differences in therapeutic goals, culture, analgesic regulations and treatment durations may contribute to this apparent difference.

摘要

背景

了解不同国家的镇痛药使用情况,可以为改善养老院患者的药理学疼痛管理提供信息。

目的

比较澳大利亚和日本养老院居民的镇痛药使用模式;并探讨澳大利亚和日本医护人员对镇痛药使用的看法。

方法

第一部分是 2019 年对南澳大利亚州 12 家养老院的 550 名居民和 2020 年东京的 4 家养老院的 333 名居民进行的横断面比较。第二部分是 2023 年对澳大利亚和日本医护人员(每组 8 人)进行的三次焦点小组讨论。使用世界卫生组织的“六步指南”对定性数据进行演绎内容分析。

结果

澳大利亚和日本的居民在年龄(中位数:89 岁比 87 岁)和性别(女性:73%比 73%)方面相似。总体而言,74%的澳大利亚居民和 11%的日本居民定期服用口服对乙酰氨基酚、非甾体抗炎药或阿片类药物。澳大利亚和日本的医护人员描述了个体化疼痛管理和一线使用对乙酰氨基酚。澳大利亚的参与者描述了他们的治疗目标是缓解疼痛,并报告经常定期开处方镇痛药。日本的参与者描述了他们的治疗目标是尽量减少疼痛对日常活动的影响,并报告经常短期开处方镇痛药,以应对疼痛发作。日本的参与者描述了限制养老院非癌性疼痛使用阿片类药物的规定。

结论

澳大利亚养老院的镇痛药使用比日本更为普遍。治疗目标、文化、镇痛药规定和治疗持续时间的差异可能导致了这一明显差异。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/959b/10898334/67a82ceec2a8/afae024f1.jpg

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