Department of Population Health.
Center for Health and Environment: Education and Research, and.
Am J Respir Crit Care Med. 2024 Jul 15;210(2):178-185. doi: 10.1164/rccm.202307-1185OC.
The share of Black or Latinx residents in a census tract remains associated with asthma-related emergency department (ED) visit rates after controlling for socioeconomic factors. The extent to which evident disparities relate to the within-city heterogeneity of long-term air pollution exposure remains unclear. To investigate the role of intraurban spatial variability of air pollution in asthma acute care use disparity. An administrative database was used to define census tract population-based incidence rates of asthma-related ED visits. We estimate the associations between census tract incidence rates and ) average fine and coarse particulate matter, nitrogen dioxide (NO), and sulfur dioxide (SO), and ) racial and ethnic composition using generalized linear models controlling for socioeconomic and housing covariates. We also examine for the attenuation of incidence risk ratios (IRRs) associated with race/ethnicity when controlling for air pollution exposure. Fine and coarse particulate matter and SO are all associated with census tract-level incidence rates of asthma-related ED visits, and multipollutant models show evidence of independent risk associated with coarse particulate matter and SO. The association between census tract incidence rate and Black resident share (IRR, 1.51 [credible interval (CI), 1.48-1.54]) is attenuated by 24% when accounting for air pollution (IRR, 1.39 [CI, 1.35-1.42]), and the association with Latinx resident share (IRR, 1.11 [CI, 1.09-1.13]) is attenuated by 32% (IRR, 1.08 [CI, 1.06-1.10]). Neighborhood-level rates of asthma acute care use are associated with local air pollution. Controlling for air pollution attenuates associations with census tract racial/ethnic composition, suggesting that intracity variability in air pollution could contribute to neighborhood-to-neighborhood asthma morbidity disparities.
在控制社会经济因素后,普查区的黑人和拉丁裔居民比例仍然与哮喘相关的急诊就诊率相关。显然,这种差异在多大程度上与城市内长期空气污染暴露的异质性有关尚不清楚。本研究旨在探讨城市内空气污染空间变异性在哮喘急性护理利用差异中的作用。
使用行政数据库定义了基于人口的哮喘相关急诊就诊率的普查区人口发生率。我们使用广义线性模型估计了普查区发病率与)平均细颗粒物和粗颗粒物、二氧化氮(NO)和二氧化硫(SO)之间的关联,以及)使用控制社会经济和住房协变量的种族和民族构成。我们还检查了当控制空气污染暴露时,与种族/民族相关的发病率风险比(IRR)的衰减情况。
细颗粒物和粗颗粒物以及 SO 均与哮喘相关急诊就诊率的普查区水平相关,多污染物模型显示出与粗颗粒物和 SO 相关的独立风险证据。当考虑到空气污染时,普查区发病率与黑人群体比例之间的关联(IRR,1.51[置信区间(CI),1.48-1.54])降低了 24%(IRR,1.39[CI,1.35-1.42]),与拉丁裔居民比例之间的关联(IRR,1.11[CI,1.09-1.13])降低了 32%(IRR,1.08[CI,1.06-1.10])。
哮喘急性护理使用的邻里水平与当地空气污染有关。控制空气污染可降低与普查区种族/民族构成的关联,表明城市内空气污染的变异性可能导致邻里间哮喘发病率差异。