He Yu-Qi, Zhang Pan, Mao Yang-Ke, Li Si-Yang, Zeng Fang, Yin Tao
Acupuncture-moxibustion and Tuina School, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China.
Acupuncture-moxibustion and Brain Science Research Center, Chengdu University of Traditional Chinese Medicine, Chengdu 611137.
Zhen Ci Yan Jiu. 2024 Feb 25;49(2):192-197. doi: 10.13702/j.1000-0607.20221289.
Neuroimaging technology provides objective and visualized research tool to study the mechanisms of acupuncture effects. Building on a systematic review of previous clinical studies on acupuncture treatment for functional dyspepsia using neuroimaging technology, this paper summarizes and synthesizes past researches from 4 aspects: acupoint-specific effects, factors influencing the effects, different physiological responses, and predictive factors for acupuncture efficacy. It suggests that acupuncture treatment for FD involves central integration with disease-targeted (acupuncture treatment can target and regulate abnormal brain functional activity patterns in patients with FD), meridian-specific (stimulation of specific acupuncture points along the stomach meridian can significantly regulate abnormal brain functional activity patterns in FD patients), and dynamic conditional features(the effects of acupuncture treatment for FD are influenced by multiple factors). Lastly, considering the current research status, this paper outlines prospects in terms of research subjects, influencing factors, and result validation, aiming to provide references for future in-depth research.
神经影像学技术为研究针刺效应机制提供了客观、可视化的研究工具。在对以往运用神经影像学技术进行针刺治疗功能性消化不良的临床研究进行系统综述的基础上,本文从穴位特异性效应、影响效应的因素、不同生理反应以及针刺疗效的预测因素4个方面对既往研究进行总结和综合。研究表明,针刺治疗FD涉及中枢整合与疾病靶向性(针刺治疗可靶向并调节FD患者异常的脑功能活动模式)、经络特异性(沿胃经刺激特定穴位可显著调节FD患者异常的脑功能活动模式)以及动态条件特征(针刺治疗FD的效应受多种因素影响)。最后,结合当前研究现状,本文从研究对象、影响因素和结果验证等方面对未来研究进行了展望,旨在为今后的深入研究提供参考。