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棘突融合对腰椎管狭窄症棘突截骨术后2年临床疗效的影响:来自NORDSTEN研究的二次分析

The Influence of Spinous Process Union on Clinical Outcomes After Spinous Process Osteotomy for Lumbar Spinal Stenosis After 2 Years: A Secondary Analysis From the NORDSTEN-Study.

作者信息

Hagerup Sondre, Brox Jens Ivar, Banitalebi Hasan, Indrekvam Kari, Myklebust Tor Åge, Hermansen Erland

机构信息

Department of Orthopedic Surgery, Ålesund Hospital, Møre and Romsdal Hospital Trust, Norway, Europe

Institute of Clinical Medicine, University of Oslo, Oslo, Norway, Europe.

出版信息

Int J Spine Surg. 2024 Feb 27;18(1):47-53. doi: 10.14444/8576.

Abstract

BACKGROUND

Lumbar spinal stenosis is a prevalent and increasingly important cause of low back pain, leg pain, and walking impairment. Minimally invasive decompressive techniques such as spinous process (SP) osteotomy have become more common in recent years. The main aim of this study was to investigate the proportion of complete SP union and whether complete radiological healing after the osteotomy is associated with superior clinical outcome after 2 years.

METHODS

In this retrospective cohort study, 149 patients were included from the Spinal Stenosis Trial, a part of the NORwegian Degenerative spondylolisthesis and spinal STENosis study. Computed tomography imaging was performed 2 years postoperatively. The number of osteotomies and the number of SP unions were recorded. Patients were divided into groups based on the degree of union: nonunion, partial union, and complete union. Rate of success (>30% improvement in Oswestry Disability Index [ODI]) and mean change in ODI were the primary outcome measures. We compared the differences between baseline and follow-up between the Degree of Union groups.

RESULTS

The study included 102 of 149 eligible patients. Ten patients (9.8%) were classified as having nonunion, 15 (14.7%) as having partial union, and 77 (75.5%) as having complete union. Of the 155 osteotomies, there were 122 classified as union (77%). The success rate was 74%, with no influence of SP union. The mean change in the ODI was -20.1 (95% CI -37.0, 14.2) with no influence of SP union.

CONCLUSIONS

We found no influence of SP union, classified by computed tomography, on clinical outcome 2 years after SP osteotomy in patients with lumbar spinal stenosis.

CLINICAL RELEVANCE

Supplying useful information about SPO to assist surgeons in the choice of decompressive technique.

摘要

背景

腰椎管狭窄症是导致腰痛、腿痛和行走障碍的常见且日益重要的原因。近年来,诸如棘突(SP)截骨术等微创减压技术已变得更为普遍。本研究的主要目的是调查SP完全愈合的比例,以及截骨术后的完全影像学愈合是否与2年后更好的临床结局相关。

方法

在这项回顾性队列研究中,纳入了来自挪威退行性腰椎滑脱和腰椎管狭窄症研究一部分的腰椎管狭窄症试验中的149例患者。术后2年进行计算机断层扫描成像。记录截骨术的数量和SP愈合的数量。根据愈合程度将患者分为几组:未愈合、部分愈合和完全愈合。成功比例(奥斯威斯功能障碍指数[ODI]改善>30%)和ODI的平均变化是主要结局指标。我们比较了愈合程度组之间基线和随访的差异。

结果

该研究纳入了149例符合条件患者中的102例。10例患者(9.8%)被分类为未愈合,15例(14.7%)为部分愈合,77例(75.5%)为完全愈合。在155例截骨术中,有122例被分类为愈合(77%)。成功率为74%,不受SP愈合的影响。ODI的平均变化为-20.1(95%可信区间-37.0,14.2),不受SP愈合的影响。

结论

我们发现,对于腰椎管狭窄症患者,术后2年通过计算机断层扫描分类的SP愈合对SP截骨术的临床结局没有影响。

临床意义

提供有关SP截骨术的有用信息,以协助外科医生选择减压技术。

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