SUNY Downstate Health Sciences University, 450 Clarkson Ave, Brooklyn, NY, 11203, USA.
J Community Health. 2024 Dec;49(6):954-958. doi: 10.1007/s10900-024-01336-7. Epub 2024 Feb 27.
Major depressive disorder (MDD) is a common mental health disorder with a lifetime prevalence of 20.6% among United States (US) adults. Multiple US surveys have shown a consistently higher burden of mental health struggles among lesbian, gay, bisexual, trans, and questioning (LGBTQ+) adults compared to non-LGBTQ+ adults. However, it is not known whether diagnosis and treatment for those adults who do report symptoms of MDD differ based on sexual orientation. We test for differences in prevalence, diagnosis, and treatment of MDD in sexual minorities using appropriate multivariable logistic regression using the New York City Health and Nutrition Examination Survey (NYC HANES). About 10% of NYC adults (≥ 20 years old) self-identify as a sexual minority and 8.5% of adults in NYC have MDD based on the Patient Health Questionnaire (PHQ-9) score. Significantly higher proportion of sexual minorities in NYC have depression compared to non-sexual minorities (17.7% vs. 7.6%, p = 0.01). In the multivariable model, sexual minorities were 2.33 (CI = [1.24-4.39], p = 0.009) times more likely to have depression compared to non-sexual minorities. Additionally, people with multimorbidity were more likely to be diagnosed for depression (OR = 3.78, CI = [1.33, 10.75], p = 0.013). Disparities exist in the prevalence, diagnosis, and treatment of MDD in NYC adults. Targeted outreach toward the LGBTQ + community should be considered by public health officials when designing primary and secondary prevention programs for depression.
重度抑郁症（MDD）是一种常见的精神健康障碍，在美国成年人中终身患病率为 20.6%。多项美国调查显示，与非 LGBTQ+成年人相比，女同性恋、男同性恋、双性恋、跨性别和 questioning（LGBTQ+）成年人的心理健康问题负担更重。然而，目前尚不清楚是否根据性取向的不同，那些报告有 MDD 症状的成年人的诊断和治疗方法有所不同。我们使用适当的多变量逻辑回归方法，使用纽约市健康和营养检查调查（NYC HANES），在性少数群体中测试 MDD 的患病率、诊断和治疗差异。约有 10%的纽约市成年人（≥ 20 岁）自我认同为性少数群体，根据患者健康问卷（PHQ-9）评分，纽约市有 8.5%的成年人患有 MDD。与非性少数群体相比，纽约市性少数群体的抑郁比例明显更高（17.7%对 7.6%，p=0.01）。在多变量模型中，性少数群体患抑郁症的可能性是性少数群体的 2.33 倍（CI=[1.24-4.39]，p=0.009）。此外，患有多种合并症的人更有可能被诊断为抑郁症（OR=3.78，CI=[1.33,10.75]，p=0.013）。在纽约市成年人中，MDD 的患病率、诊断和治疗存在差异。公共卫生官员在设计抑郁症的一级和二级预防计划时，应考虑针对 LGBTQ+社区的定向外展。
