Wang Yu-Yong, Zheng Xiang-Yi, Mao Qi-Qi, Xie Li-Ping
Department of Urology, The First Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou, China.
Department of Urology, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Arch Med Sci. 2020 Apr 27;20(1):133-137. doi: 10.5114/aoms.2020.94681. eCollection 2024.
Laparoscopic radical prostatectomy (LRP) has become a common option for the treatment of prostate cancer. The aim of our study was to examine whether LRP performed within 12 weeks of transurethral resection of the prostate (TURP) is associated with surgical difficulty or outcomes.
A single-institutional retrospective analysis was performed on patients who underwent LRP for incidental prostate cancer after TURP between July 2009 and December 2017. The interval between TURP and LRP was determined and patients with intervals of ≤ 12 weeks were compared to those with intervals of > 12 weeks. Patient characteristics, perioperative, pathological, and postoperative functional outcomes were analyzed to determine statistically significant differences between the 2 groups. Multivariable analyses were performed to determine whether the interval between TURP and LRP was a significant independent predictor of these outcomes.
A total of 56 incidental prostate cancer patients detected by TURP were included in this study. No significant differences were detected in estimated blood loss, operative duration, postoperative length of stay, and rate of positive margin, Gleason score upgrading, major complications, incontinence and prostate-specific antigen (PSA) recurrence in patients with a TURP to LRP interval above and below 12 weeks. The TURP to LRP interval was not an independent predictor of outcomes during or after LRP.
Our results showed that performing LRP within 12 weeks after TURP does not adversely influence surgical difficulty or outcomes.
腹腔镜根治性前列腺切除术(LRP)已成为治疗前列腺癌的常用选择。我们研究的目的是探讨在经尿道前列腺切除术(TURP)后12周内进行的LRP是否与手术难度或手术结果相关。
对2009年7月至2017年12月期间因TURP术后偶然发现前列腺癌而接受LRP的患者进行单机构回顾性分析。确定TURP与LRP之间的间隔时间,并将间隔时间≤12周的患者与间隔时间>12周的患者进行比较。分析患者特征、围手术期、病理和术后功能结果,以确定两组之间的统计学显著差异。进行多变量分析以确定TURP与LRP之间的间隔时间是否是这些结果的显著独立预测因素。
本研究共纳入56例经TURP检测出的偶然前列腺癌患者。TURP至LRP间隔时间在12周以上和以下的患者,在估计失血量、手术持续时间、术后住院时间、切缘阳性率、Gleason评分升级、主要并发症、尿失禁和前列腺特异性抗原(PSA)复发率方面均未检测到显著差异。TURP至LRP间隔时间不是LRP期间或术后结果的独立预测因素。
我们的结果表明,在TURP后12周内进行LRP不会对手术难度或手术结果产生不利影响。