Sharma Varun, Yadav Himanshu P, Prakash Abhishek, Yadav Namrata, Kumar Mukesh, Abbas Haider
Cardiac Anesthesia, Chandan Hospital, Lucknow, IND.
Anesthesiology, Kalyan Singh Superspeciality Cancer Institute, Lucknow, IND.
Cureus. 2024 Feb 26;16(2):e55005. doi: 10.7759/cureus.55005. eCollection 2024 Feb.
Introduction Difficulties with tracheal intubation contribute to the morbidity and mortality associated with anesthesia. Suggested predictors for difficult airway include, history of obstructive sleep apnea, high Mallampati score, elderly, male, short neck, and high Wilson score. However, none of these has high diagnostic accuracy particularly in obese population. Parameters used to quantify obesity such as Body Mass Index(BMI), mid arm circumference, skin fold thickness, etc. have not been used as independent predictors of difficult airway. This study has been designed to evaluate the accuracy of commonly used tools to assess difficult airway and to test other obesity markers as scale for assessing difficult airway i.e. Bag mask ventilation grade ≥3 or Cormack-Lehane Grade≥3 on Direct Laryngoscopy or number of intubation attempts ≥3. Aim To assess BMI, Mallampati grading, Neck circumference and Thyromental distance as predictors of difficult airway in obese patients and to validate neck circumference to thyromental distance ratio and skin fold thickness as a tool for assessment of difficult airway (Bag mask ventilation grade ≥3 or Cormack-Lehane Grade≥3 on Direct Laryngoscopy or number of intubation attempts ≥3.) in obese patients. Methods This prospective observational study was carried out on 51 obese patients (as per BMI) of ASA grade II, either sex, aged 23 to 57 years posted for elective surgery under general anesthesia with endotracheal intubation. After subjective assessment of difficult airway following data sets and variables were obtained - sex, weight, height, body mass index (BMI), Modified Mallampati class (MPG), Cormack-Lehane (CL) grade, adequacy of bag mask ventilation (BMV), number of endotracheal intubation attempts, patient's neck circumference (NC), thyromental distance (TMD), waist-hip ratio (WHR) and Skin fold thickness. The observations made during the study were statistically analyzed and correlated as predictors for difficult airway. Result Correlation of MPG to CL-grade (r-0.41, p-0.003), BMV (r-0.31, p-0.028) & No. of intubation attempts (r-0.37, p-0.007) was mild & statistically significant. Correlation of Neck Circumference with CL-grade (r-0.57, p-0.000), & No. of intubation attempts (r-0.62, p-0.000), found moderate & statistically significant, & with BMV was mild and statistically significant (r-0.48, p-0.000). Correlation of Thyromental Distance to CL-grade (r-0.65, p-0.000), BMV (r-0.70, p-0.000) & No. of intubation attempts (r-0.61, p-0.000) was moderate & statistically significant. Correlation of BMI to CL-grade (r-0.11, p-0.428), BMV (r-0.04, p-0.757) & No. of intubation attempts (r-0.16, p-0.257) was weak & not significant. Skin Fold Thickness showed no significant association with Difficult airway i.e., CL Grade (p-0.478), BMV (p-0.101), and No. of intubation attempts (p-0.143). Correlation of NC/TMD ratio with BMV (r-0.74, p-0.000), CL-grade (r-0.76, p-0.000), & No. of intubation attempts (r-0.77, p-0.000) was moderate & statistically significant. Conclusion NC, TMD and NC/TMD Ratio depicted a close association with airway difficulty in obese patients. Obesity grade is a risk factor for difficult airway but predictors of obesity including Skin Fold Thickness, individually did not show association with difficult airway (small sample size may be a limiting factor). None of the commonly performed tests alone has proven to be adequate in predicting difficult intubation in the obese population.
引言
气管插管困难会增加麻醉相关的发病率和死亡率。提示气道困难的预测因素包括阻塞性睡眠呼吸暂停病史、高 Mallampati 评分、老年、男性、短颈和高 Wilson 评分。然而,这些因素均无较高的诊断准确性,尤其是在肥胖人群中。用于量化肥胖的参数,如体重指数(BMI)、上臂中部周长、皮褶厚度等,尚未被用作气道困难的独立预测指标。本研究旨在评估常用工具评估气道困难的准确性,并测试其他肥胖标志物作为评估气道困难的指标,即面罩通气分级≥3 级或直接喉镜检查时 Cormack-Lehane 分级≥3 级或插管尝试次数≥3 次。
目的
评估 BMI、Mallampati 分级、颈围和甲颏距离作为肥胖患者气道困难的预测指标,并验证颈围与甲颏距离之比和皮褶厚度作为评估肥胖患者气道困难(面罩通气分级≥3 级或直接喉镜检查时 Cormack-Lehane 分级≥3 级或插管尝试次数≥3 次)的工具。
方法
本前瞻性观察性研究对 51 例 ASA II 级肥胖患者(根据 BMI)进行,年龄 23 至 57 岁,性别不限,拟行全身麻醉下气管插管的择期手术。在对气道困难进行主观评估后,获取以下数据集和变量:性别、体重、身高、体重指数(BMI)、改良 Mallampati 分级(MPG)、Cormack-Lehane(CL)分级、面罩通气的充分性(BMV)、气管插管尝试次数、患者颈围(NC)、甲颏距离(TMD)、腰臀比(WHR)和皮褶厚度。对研究期间的观察结果进行统计学分析,并将其作为气道困难的预测指标进行相关性分析。
结果
MPG 与 CL 分级的相关性(r = 0.41,p = 0.003)、BMV(r = 0.31,p = 0.028)和插管尝试次数(r = 0.37,p = 0.007)为轻度且具有统计学意义。颈围与 CL 分级的相关性(r = 0.57,p = 0.000)和插管尝试次数(r = 0.62,p = 0.000)为中度且具有统计学意义,与 BMV 的相关性为轻度且具有统计学意义(r = 0.48,p = 0.000)。甲颏距离与 CL 分级的相关性(r = 0.65,p = 0.000)、BMV(r = 0.70,p = 0.000)和插管尝试次数(r = 0.61,p = 从 0.000)为中度且具有统计学意义。BMI 与 CL 分级的相关性(r = 0.11,p = 0.428)、BMV(r = 0.04,p = 0.757)和插管尝试次数(r = 0.16,p = 0.257)较弱且无统计学意义。皮褶厚度与气道困难即 CL 分级(p = 0.478)、BMV(p = 0.101)和插管尝试次数(p = 0.143)无显著相关性。NC/TMD 比值与 BMV 的相关性(r = 0.74,p = 0.000)、CL 分级(r = 0.76,p = 0.000)和插管尝试次数(r = 0.77,p = 0.000)为中度且具有统计学意义。
结论
NC、TMD 和 NC/TMD 比值与肥胖患者的气道困难密切相关。肥胖分级是气道困难的一个危险因素,但包括皮褶厚度在内的肥胖预测指标单独与气道困难无相关性(样本量小可能是一个限制因素)。单独的常用检查均未被证明足以预测肥胖人群的插管困难。