Sinha Aparna, Jayaraman Lakshmi, Punhani Dinesh
Department of Anesthesia, Institute of Minimal Access, Metabolic and Bariatric Surgery, Max Super Speciality Hospital, Saket, New Delhi, India.
J Anaesthesiol Clin Pharmacol. 2020 Jan-Mar;36(1):25-30. doi: 10.4103/joacp.JOACP_164_19. Epub 2020 Feb 18.
We aimed to redefine the preoperative factors that may challenge the airway and safe apnea time (SAT) in the obese.
We analyzed 834 patients with body mass index (BMI) >35 kg/m for their difficult airway score (DASc). DASc is a consolidation of measures of difficult airway like mask ventilation, difficult intubation, change of device, and number of personnel required. DASc varied from "0" no difficulty to "12" serious difficulty and DASc ≥6 was considered difficult. Preoperative parameters - neck circumference (NC), BMI, STOPBANG score, Mallampati score, obstructive sleep apnea grade, and waist circumference- were assessed.
Receiver operating characteristic curve was used to identify risk factors for obese patients at DASc ≥6. The Youden index (for the best threshold, with highest sensitivity and specificity) was BMI 45 kg/m and NC 44.5 cm. Their absence had an 81% negative predictive value to include a difficult airway, while their presence had a positive predictive value of 55%. This further has sensitivity of 66% and specificity of 73%. The mean SAT (256 ± 6 s) was inversely related to DASc ( < 0.001).
This study demonstrates that BMI and NC have a strong association with difficult airway in obese patients and are inversely related to SAT. Amongst these NC is the single most important predictor of difficult airway in obese and should be used as a screening tool.
我们旨在重新定义可能对肥胖患者气道和安全无呼吸时间(SAT)构成挑战的术前因素。
我们分析了834例体重指数(BMI)>35 kg/m²的患者的困难气道评分(DASc)。DASc是对困难气道的各项指标的综合考量,如面罩通气、困难插管、设备更换以及所需人员数量。DASc的范围从“0”(无困难)到“12”(严重困难),DASc≥6被视为困难气道。评估了术前参数——颈围(NC)、BMI、STOPBANG评分、马兰帕蒂评分、阻塞性睡眠呼吸暂停分级和腰围。
采用受试者工作特征曲线来确定DASc≥6的肥胖患者的危险因素。约登指数(用于确定最佳阈值,具有最高敏感性和特异性)对应的BMI为45 kg/m²,颈围为44.5 cm。不存在这些因素时,排除困难气道的阴性预测值为81%,而存在这些因素时,阳性预测值为55%。这进一步得出敏感性为66%,特异性为73%。平均SAT(256±6秒)与DASc呈负相关(<0.001)。
本研究表明,BMI和颈围与肥胖患者的困难气道密切相关,且与SAT呈负相关。其中,颈围是肥胖患者困难气道的唯一最重要预测指标,应用作筛查工具。