印度患者中使用局部药物递送治疗种植体周围炎
Management of peri-implantitis using local drug delivery among Indian patients.
作者信息
Khare Shilpi, Doda Hitika P, Dubey Vanya, Sutaria Shreyansh, Nath Shib Kumar, Bhatt Drishti, Kumar Santosh, Desai Prachi
机构信息
Department of Prosthodontics, Bhabha College of Dental Sciences, Bhopal, M.P., India.
Midtown Dental Group, New Jersey, USA.
出版信息
Bioinformation. 2023 Dec 31;19(13):1301-1306. doi: 10.6026/973206300191301. eCollection 2023.
Abstract
It is of interest to compare 0.2% chlorhexidine gel, 0.2% chlorhexidine chip, minocycline microspheres and slow-release doxycycline gel and tetracycline fibers as drug delivery systems in the management of peri-implantitis. The study comprised of 105 Indian participants who had a minimum of one dental implant with a probing depth of 4 mm, along with exudate and/or bleeding upon probing along with the presence of potentially harmful germs. The use of minocycline microspheres and 0.2% chlorhexidine gel resulted in significant improvements in probing depths at 1 month, 3 months and 6 months and all treatments showed decline in the indicator bacteria. Thus, minocycline microspheres and 0.2% chlorhexidine gel is useful as an adjuvant for mechanical debridement in management of peri-implantitis.
摘要
比较0.2%氯己定凝胶、0.2%氯己定芯片、米诺环素微球、缓释强力霉素凝胶和四环素纤维作为药物递送系统在种植体周围炎治疗中的效果很有意义。该研究包括105名印度参与者，他们至少有一颗种植体，探诊深度为4毫米，探诊时有渗出物和/或出血，同时存在潜在有害细菌。使用米诺环素微球和0.2%氯己定凝胶在1个月、3个月和6个月时探诊深度有显著改善，所有治疗均显示指示菌数量下降。因此，米诺环素微球和0.2%氯己定凝胶可作为种植体周围炎治疗中机械清创的辅助手段。
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