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营养不良性皮肤钙化症导致慢性静脉功能不全患者伤口不愈合

Dystrophic Calcinosis Cutis Leading to a Nonhealing Wound in a Patient with Chronic Venous Insufficiency.

作者信息

Kyoung Jun, Caudill Jennifer, Workman Lauren, Simman Richard

机构信息

From the College of Medicine and Life Sciences, University of Toledo, Toledo, Ohio.

Department of Surgery, University of Toledo, College of Medicine and Life Sciences, Toledo, Ohio.

出版信息

Plast Reconstr Surg Glob Open. 2024 Feb 27;12(2):e5641. doi: 10.1097/GOX.0000000000005641. eCollection 2024 Feb.

Abstract

The presence of bony-appearing fragments and calcifications appearing superficially in a chronic, nonhealing wound raises suspicion for osteomyelitis. When radiological imaging and tissue biopsy of the lesion return negative for osteomyelitis, however, the differentials must be widened to successfully manage and heal a chronic wound. In this report, we discuss a case of an 80-year-old morbidly obese woman with a history of chronic venous insufficiency, hereditary hemochromatosis, and squamous cell carcinoma who presented to the wound clinic with a 5-month history of a nonhealing wound with bony-appearing fragments and calcifications on her left anterior leg status postbiopsy during routine skin examination. Upon clinical correlation with laboratories and imaging, it was determined that the cause of her nonhealing wound was due to dystrophic calcinosis cutis.

摘要

在慢性不愈合伤口表面出现骨样碎片和钙化提示存在骨髓炎的可能。然而,当病变的放射影像学检查和组织活检结果排除骨髓炎时,就必须扩大鉴别诊断范围,以成功处理和治愈慢性伤口。在本报告中,我们讨论了一例80岁的病态肥胖女性病例,她有慢性静脉功能不全、遗传性血色素沉着症和鳞状细胞癌病史,因左小腿前侧一个5个月不愈合的伤口前来伤口诊所就诊,该伤口在常规皮肤检查活检后可见骨样碎片和钙化。经与实验室检查及影像学结果进行临床关联分析,确定其伤口不愈合的原因是营养不良性皮肤钙化。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d94d/10898656/8ef37d5ebf1c/gox-12-e5641-g001.jpg

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