Derouet Cyril, Kissling Sébastien, Roth Beat, Bonny Olivier, Schwotzer Nora
Service de néphrologie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Service d'urologie, Centre hospitalier universitaire vaudois, 1011 Lausanne.
Rev Med Suisse. 2024 Feb 28;20(863):436-440. doi: 10.53738/REVMED.2024.20.863.436.
Kidney stone is one of the most frequent disorders of the urinary tract. Once the stone has passed, the management should be oriented on prevention. If changes in lifestyle and diet should be implemented in a true therapeutic education of the patient, prescription of drugs has been recently challenged by the NOSTONE trial. This randomized controlled trial did not show any benefit of hydrochlorothiazide in the prevention of recurrence of kidney stone event in patients with calcium-containing stone. Therefore, prescription of thiazide in the sole purpose of decreasing kidney stone recurrence should be limited and the risk/benefit of this treatment should be carefully balanced for each case.
肾结石是最常见的泌尿系统疾病之一。一旦结石排出，治疗应侧重于预防。如果在对患者进行真正的治疗性教育中应改变生活方式和饮食，那么药物处方最近受到了NOSTONE试验的挑战。这项随机对照试验并未显示氢氯噻嗪在预防含钙结石患者肾结石事件复发方面有任何益处。因此，仅为降低肾结石复发而使用噻嗪类药物的处方应受到限制，并且应针对每个病例仔细权衡这种治疗的风险/益处。
