Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia School of Medicine, Charlottesville, Virginia.
Division of Medical Toxicology, Department of Emergency Medicine, University of Virginia School of Medicine, Charlottesville, Virginia.
J Adolesc Health. 2024 May;74(5):1053-1056. doi: 10.1016/j.jadohealth.2024.01.027. Epub 2024 Feb 26.
We describe trends in psilocybin exposures among adolescents and young adults as reported to US poison centers over the past decade.
We queried the National Poison Data System for cases involving psilocybin during January 1, 2013-December 31, 2022. Persons aged 13-25 years were included. We examined exposures to psilocybin by demographics, clinical effects, level of care, and medical outcome.
During the 10-year study period, 4,055 psilocybin-involved exposures were reported among adolescents and young adults, 2,667 (65.8%) being single substance exposures. Most single substance cases received medical attention (adolescents: 75.3% [n = 1,176], young adults: 72.1% [n = 797]). We did not find significant change in the number of cases during 2013-2018. Cases started increasing in 2019. In 2022, cases more than tripled among adolescents and more than doubled among young adults, compared to 2018 (p < .0001).
Continued national surveillance is critical to determine the impact of psilocybin exposures on youth as it becomes increasingly available.
我们描述了过去十年中向美国毒物中心报告的青少年和年轻成年人中迷幻蘑菇暴露的趋势。
我们在 2013 年 1 月 1 日至 2022 年 12 月 31 日期间查询了国家毒物数据系统，以寻找涉及迷幻蘑菇的病例。包括年龄在 13-25 岁的人群。我们通过人口统计学、临床影响、护理水平和医疗结果来检查迷幻蘑菇的暴露情况。
在 10 年的研究期间，报告了 4055 例青少年和年轻成年人的迷幻蘑菇暴露病例，其中 2667 例（65.8%）为单一物质暴露。大多数单一物质病例都接受了医疗关注（青少年：75.3%[n=1176]；年轻人：72.1%[n=797]）。我们没有发现 2013-2018 年期间病例数量的显著变化。2019 年开始增加。与 2018 年相比，2022 年青少年的病例数增加了两倍多，年轻人的病例数增加了一倍多（p<0.0001）。
随着迷幻蘑菇的使用越来越广泛，持续的全国性监测对于确定其对青少年的影响至关重要。
