Malacinski G M, Barone D
J Embryol Exp Morphol. 1985 Nov;89 Suppl:53-68.
As a model system for understanding the role sperm extragenic components might play in early embryogenesis the genetics and phenotype of the ts-1 axolotl (Ambystoma mexicanum) mutant gene are reviewed. That mutant gene displays parental effects. It exhibits both maternal (egg-mediated) as well as paternal (sperm-mediated) phenotypic effects. A variety of possible modes of action of the ts-1 gene are reviewed. Comparisons of various precedents to the ts-1 genetic data are made. In addition, novel models which account for the ts-1 phenotypic data are presented.
作为一个用于理解精子外基因成分在早期胚胎发育中可能发挥的作用的模型系统，本文综述了ts-1美西钝口螈（墨西哥钝口螈）突变基因的遗传学和表型。该突变基因表现出亲本效应。它既表现出母本（卵子介导）效应，也表现出父本（精子介导）表型效应。本文综述了ts-1基因的各种可能作用模式。对ts-1遗传数据的各种先例进行了比较。此外，还提出了解释ts-1表型数据的新模型。
