Pento Speech and Hearing Centers, Leeuwarden, The Netherlands.
Dept. Neonatology, Isala Clinics, Zwolle, The Netherlands.
PLoS One. 2024 Feb 28;19(2):e0297363. doi: 10.1371/journal.pone.0297363. eCollection 2024.
The aim of this study is to assess the neonatal click Auditory Brainstem Response (ABR) results in relation to the subsequently determined mean hearing loss (HL) over 1, 2 and 4 kHz, as well as over 2 and 4 kHz.
Between 2004-2009, follow-up data were collected from Visual Reinforcement Audiometry (VRA) at 1 and 2 years and playaudiometry at 4 and 8 years of newborns who had failed neonatal hearing screening in the well-baby clinics and who had been referred to a single Speech and Hearing center. Hearing Level data were compared with ABR threshold-levels established during the first months of life. The Two One-Sided Tests equivalence procedure for paired means was applied, using a region of similarity equal to 10 dB.
Initially, in 135 out of 172 children referred for diagnostic procedures hearing loss was confirmed in the neonatal period. In 106/135 of the HL children the eight-year follow-up was completed. Permanent conductive HL was established in 5/106 cases; the hearing thresholds were predominantly stable over time. Temporary conductive HL was found in 48/106 cases and the loss disappeared by 4 years of age at the latest. Sensorineural hearing loss (SNHL) was found in 53/106 cases, of which 13 were unilateral and 40 bilateral. ABR levels were equivalent (within a 10 dB range) to VRA levels at age 1 and 2 and play audiometry levels at age 4 and 8, both when VRA and play audiometry were averaged over both frequency ranges.
Long term follow-up data of children with SNHL suggest that the initial click ABR level established in the first months of life, are equivalent to the hearing threshold measured at the age of 1, 2, 4 and 8 years for both mean frequency ranges. Click ABR can reliably be used as starting point for long-term hearing rehabilitation.
本研究旨在评估新生儿 click 听性脑干反应(ABR)结果与随后在 1、2 和 4 kHz 以及 2 和 4 kHz 确定的平均听力损失(HL)之间的关系。
在 2004 年至 2009 年期间,从视觉强化测听法(VRA)在 1 岁和 2 岁以及玩耍测听法在 4 岁和 8 岁处收集在常规婴儿诊所进行新生儿听力筛查失败并转介至单一言语和听力中心的新生儿的随访数据。听力水平数据与生命最初几个月建立的 ABR 阈值水平进行比较。使用相似性区域等于 10 dB 的双侧均值的两单侧检验等效性程序进行应用。
最初,在 172 名转介进行诊断程序的儿童中,有 135 名在新生儿期确诊有听力损失。在 106/135 名 HL 儿童中完成了八年随访。5/106 例确定为永久性传导性 HL,听力阈值随时间推移基本稳定。48/106 例发现为暂时性传导性 HL,最晚在 4 岁时听力损失消失。53/106 例发现感音神经性听力损失(SNHL),其中 13 例为单侧,40 例为双侧。ABR 水平与 VRA 在 1 岁和 2 岁时以及玩耍测听法在 4 岁和 8 岁时的水平等效(在 10 dB 范围内),当 VRA 和玩耍测听法在两个频率范围内平均时也是如此。
SNHL 儿童的长期随访数据表明,在生命最初几个月建立的初始 click ABR 水平与在 1、2、4 和 8 岁时测量的平均频率范围内的听力阈值等效。click ABR 可可靠地用作长期听力康复的起点。