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首例由红杆菌引起的坏死性筋膜炎和败血症。

First Case of Necrotizing Fasciitis and Septicemia Caused by Pigmentibacter ruber.

机构信息

Division of Clinical Laboratory, Gifu University Hospital, Japan.

Gifu University Center for Conservation of Microbial Genetic Resource, Japan.

出版信息

Jpn J Infect Dis. 2024 Jul 23;77(4):244-246. doi: 10.7883/yoken.JJID.2023.370. Epub 2024 Feb 29.

Abstract

We report the first case of necrotizing fasciitis caused by Pigmentibacter ruber. The isolated strain could not be identified by biochemical characterization or matrix-assisted laser desorption/ionization time-of-flight mass spectrometry but was identified as P. ruber by 16S ribosomal RNA and whole-genome sequencing. Although much remains unknown about the pathogenicity of this bacterial species in humans, it has been shown to cause life-threatening infections such as septicemia and necrotizing fasciitis. Because the isolate was highly resistant to β-lactams, it was difficult to treat with antimicrobial therapy. Thus, further documentation of cases and analyses are required.

摘要

我们报告了首例由红杆菌引起的坏死性筋膜炎。该分离株不能通过生化特征或基质辅助激光解吸/电离飞行时间质谱鉴定,但通过 16S 核糖体 RNA 和全基因组测序鉴定为红杆菌。尽管关于该细菌在人类中的致病性仍有许多未知,但它已被证明会引起危及生命的感染,如败血症和坏死性筋膜炎。由于该分离株对β-内酰胺类药物高度耐药,因此用抗菌治疗很难治愈。因此,需要进一步记录病例并进行分析。

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