Division of Clinical Laboratory, Gifu University Hospital, Japan.
Gifu University Center for Conservation of Microbial Genetic Resource, Japan.
Jpn J Infect Dis. 2024 Jul 23;77(4):244-246. doi: 10.7883/yoken.JJID.2023.370. Epub 2024 Feb 29.
We report the first case of necrotizing fasciitis caused by Pigmentibacter ruber. The isolated strain could not be identified by biochemical characterization or matrix-assisted laser desorption/ionization time-of-flight mass spectrometry but was identified as P. ruber by 16S ribosomal RNA and whole-genome sequencing. Although much remains unknown about the pathogenicity of this bacterial species in humans, it has been shown to cause life-threatening infections such as septicemia and necrotizing fasciitis. Because the isolate was highly resistant to β-lactams, it was difficult to treat with antimicrobial therapy. Thus, further documentation of cases and analyses are required.
我们报告了首例由红杆菌引起的坏死性筋膜炎。该分离株不能通过生化特征或基质辅助激光解吸/电离飞行时间质谱鉴定,但通过 16S 核糖体 RNA 和全基因组测序鉴定为红杆菌。尽管关于该细菌在人类中的致病性仍有许多未知,但它已被证明会引起危及生命的感染,如败血症和坏死性筋膜炎。由于该分离株对β-内酰胺类药物高度耐药,因此用抗菌治疗很难治愈。因此,需要进一步记录病例并进行分析。