Suppr超能文献

维生素 C 缺乏症可模仿凝血障碍。

Vitamin C Deficiency as a Mimicker of a Coagulation Disorder.

机构信息

Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA

Warren Alpert Medical School of Brown University, Providence, Rhode Island, USA.

出版信息

BMJ Case Rep. 2024 Feb 27;17(2):e259310. doi: 10.1136/bcr-2023-259310.

Abstract

Scurvy is caused by vitamin C deficiency and is often thought of as an ancient malady. However, it still afflicts present-day patients with insufficient nutrition, excessive alcohol consumption and disorders of absorption. Scurvy is traditionally characterised by ecchymosis, petechiae, haemorrhages, poor wound healing, myalgias and arthralgias, but it can also present with non-specific symptoms, including mood changes, fatigue, malaise and dyspnoea. Although scurvy can present with signs of excess bleeding, it does not involve blood clotting. We present a case of concurrent scurvy and pulmonary embolism in which clinical presentation and laboratory findings mimicked a coagulation disorder, resulting in delayed diagnosis and excessive resource expenditure. This case underscores the importance of obtaining an early dietary and substance use history in patients with unexplained haematological symptoms. These crucial components of history-taking can significantly reduce invasive and costly tests, resulting in quicker diagnosis and enhanced patient outcomes.

摘要

坏血病是由维生素 C 缺乏引起的,通常被认为是一种古老的疾病。然而,它仍然困扰着现今营养不足、过度饮酒和吸收障碍的患者。坏血病的传统特征是瘀斑、瘀点、出血、伤口愈合不良、肌痛和关节痛,但也可能出现非特异性症状,包括情绪变化、疲劳、不适和呼吸困难。虽然坏血病可能出现出血过多的迹象,但它并不涉及血液凝结。我们报告了一例并发坏血病和肺栓塞的病例,其临床表现和实验室检查结果类似于凝血障碍,导致诊断延迟和过度资源消耗。这个病例强调了在出现不明原因血液症状的患者中获取早期饮食和物质使用史的重要性。这些病史的关键组成部分可以显著减少侵入性和昂贵的检查,从而更快地诊断和改善患者的预后。

相似文献

1
Vitamin C Deficiency as a Mimicker of a Coagulation Disorder.
BMJ Case Rep. 2024 Feb 27;17(2):e259310. doi: 10.1136/bcr-2023-259310.
2
An orange a day keeps the doctor away: scurvy in the year 2000.
Pediatrics. 2001 Sep;108(3):E55. doi: 10.1542/peds.108.3.e55.
3
Scurvy.
Acta Dermatovenerol Croat. 2022 Jul;30(1):59-60.
4
High-dose vitamin C therapy for symptomatic deficiency in a patient with myasthenia gravis and Crohn's disease.
Nutr Clin Pract. 2022 Oct;37(5):1242-1245. doi: 10.1002/ncp.10800. Epub 2021 Nov 16.
5
A case of scurvy in Singapore in the year 2006.
Singapore Med J. 2007 Dec;48(12):1151-5.
6
Ascorbic acid deficiency: a case report.
J Dent Child (Chic). 2011 Jul;78(2):115-9.
7
[Scurvy still occurs].
Ned Tijdschr Geneeskd. 2023 Mar 29;167:D6906.
8
Scurvy in the present times: vitamin C allergy leading to strict fast food diet.
Dermatol Online J. 2016 Jan 15;22(1):13030/qt50b8w28b.
9
[Vitamin C].
Rev Prat. 2013 Oct;63(8):1091-6.

本文引用的文献

1
Scurvy: Rediscovering a Forgotten Disease.
Diseases. 2023 May 26;11(2):78. doi: 10.3390/diseases11020078.
3
Vitamin C and alcohol: a call to action.
BMJ Nutr Prev Health. 2018 Dec 5;1(1):17-22. doi: 10.1136/bmjnph-2018-000010. eCollection 2018.
4
Global Vitamin C Status and Prevalence of Deficiency: A Cause for Concern?
Nutrients. 2020 Jul 6;12(7):2008. doi: 10.3390/nu12072008.
5
Severe scurvy in an adult male without clear risk factors for nutritional deficiency.
JAAD Case Rep. 2019 Apr 1;5(4):309-311. doi: 10.1016/j.jdcr.2019.01.031. eCollection 2019 Apr.
6
Latent scurvy with tiredness and leg pain in alcoholics: An underestimated disease three case reports.
Medicine (Baltimore). 2017 Nov;96(47):e8861. doi: 10.1097/MD.0000000000008861.
7
Think about the 'C' (in custard and crackers).
Arch Dis Child Educ Pract Ed. 2018 Dec;103(6):304-306. doi: 10.1136/archdischild-2017-312993. Epub 2017 Nov 9.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验