Department of Otolaryngology-Head and Neck Surgery and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel, Department of Otolaryngology, Head and Neck Surgery, Hillel Yaffe Medical Center, Hadera, Israel, Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, Rappaport Faculty of Medicine, Technion-Israel Institute of Technology, Haifa, Israel.
Department of Otolaryngology-Head and Neck Surgery, Galilee Medical Center, Nahariya, Israel, Azrieli Faculty of Medicine, Bar-Ilan University, Safed, Israel.
Isr Med Assoc J. 2024 Jan;26(1):40-44.
Laryngopharyngeal reflux (LPR) refers to the backflow of acidic stomach content into the larynx, pharynx, and upper aerodigestive tract. The diagnosis of LPR is based on the patient's history and findings of the laryngoscopy associated with LPR. Other possible manifestations consistent with LPR symptoms include laryngeal cancer, vocal fold granulomas, Reinke's space edema, and vocal polyps. In this study, we compared the characteristics of patients with LPR symptoms and incidental laryngeal findings (ILF) in the laryngoscopic evaluation to those without ILF (WILF).
Determine the characteristics of LPR-symptomatic patients with ILF versus WILF.
In this retrospective study, we examined 160 medical charts from patients referred to the otolaryngology clinic at Galilee Medical Center for LPR evaluation 2016-2018. The reflux symptoms index (RSI), reflux finding score (RFS), and demographics of the patient were collected. All patients with a positive RSI score for LPR (RSI > 9) were included, and the profiles of patients with versus without ILF on laryngoscopy examination were compared.
Of the 160 patients, 20 (12.5%) had ILF during laryngoscopy. Most had vocal cord findings such as leukoplakia (20%), polyps (15%), and nodules (20%). Hoarseness, throat clearing, swallowing difficulty, breathing difficulties, and total RSI score were significantly higher in patients with ILF.
Evaluation of LPR symptoms may provide otolaryngologists with a tool to identify patients with other findings on fiberoptic laryngoscopy. A laryngoscopic examination should be part of the examination of every patient with LPR to enable diagnosis of incidental findings.
咽喉反流（LPR）是指酸性胃内容物反流至喉、咽和上呼吸道。LPR 的诊断基于患者的病史和与 LPR 相关的喉镜检查结果。其他与 LPR 症状一致的可能表现包括喉癌、声带肉芽肿、Reinke 空间水肿和声带息肉。在这项研究中，我们比较了 LPR 症状患者与喉镜检查中偶然发现的喉部表现（ILF）患者与无 ILF（WILF）患者的特征。
确定有 ILF 的 LPR 症状患者的特征与 WILF 患者的特征。
在这项回顾性研究中，我们检查了 2016 年至 2018 年期间因 LPR 评估而转至加利利医疗中心耳鼻喉科诊所的 160 份病历。收集了反流症状指数（RSI）、反流发现评分（RFS）和患者的人口统计学数据。所有 RSI 评分阳性（RSI > 9）的 LPR 患者均被纳入研究，比较了喉镜检查有与无 ILF 患者的特征。
在 160 名患者中，20 名（12.5%）在喉镜检查时有 ILF。大多数患者的声带表现为白斑（20%）、息肉（15%）和结节（20%）。有 ILF 的患者声音嘶哑、清嗓、吞咽困难、呼吸困难和总 RSI 评分明显更高。
评估 LPR 症状可能为耳鼻喉科医生提供一种工具，以识别纤维喉镜检查中有其他发现的患者。对于每个 LPR 患者，都应进行喉镜检查，以能够诊断偶然发现的异常。
