Department of Medicine, Surgery and Pharmacy, Sassari University, Italy.
Otolaryngology Division, Sassari University Hospital, Sassaey, Italy.
Acta Otorhinolaryngol Ital. 2024 Feb;44(1):13-20. doi: 10.14639/0392-100X-N2786.
Squamous cell carcinoma of the nasal vestibule (NV SCC) is a head and neck malignancy for which there is no established consensus on most aspects of clinical management. The purpose of this document is to give updated recommendations that incorporate recent evidence on its clinical characteristics and the high efficacy of brachytherapy as primary treatment modality.
A working group consisting of the members of the Scientific Committee for Oncology and Reconstructive Surgery of the Italian Society of Otorhinolaryngology Head and Neck Surgery and radiation oncologists expert in brachytherapy was formed to achieve a consensus.
Consensus was reached on a set of recommendations, proposing a refined anatomical definition of the nasal vestibule, a novel T staging system of the NV SCC, and brachytherapy as standard of care, with a new method for catheter implantation.
The Committee emphasises the critical role of an accurate classification in clinical practice and encourages further research to validate the novel staging system and further improve treatment strategies. Where appropriate, it is recommended that patients be referred to centres with specific experience in brachytherapy for NV SCC.
鼻腔前庭鳞状细胞癌（NV SCC）是一种头颈部恶性肿瘤，其临床管理的大多数方面尚无明确共识。本文旨在提供最新的建议，纳入关于其临床特征和近距离放疗作为主要治疗方式的高效性的最新证据。
成立了一个由意大利耳鼻喉科学会肿瘤学和重建外科学科学委员会成员以及近距离放疗专家组成的工作组，以达成共识。
就一组建议达成了共识，提出了鼻腔前庭的精细解剖定义、NV SCC 的新 T 分期系统以及近距离放疗作为标准治疗方法，同时提出了一种新的导管植入方法。
委员会强调了准确分类在临床实践中的关键作用，并鼓励进一步研究以验证新的分期系统，并进一步改进治疗策略。在适当的情况下，建议将患者转介到具有 NV SCC 近距离放疗专业经验的中心。
