对一些允许使用的食用色素在二倍体酵母中诱导基因转化的测试。

Testing of some permitted food colours for the induction of gene conversion in diploid yeast.

作者信息

Sankaranarayanan N, Murthy M S

出版信息

Mutat Res. 1979 Aug;67(4):309-14. doi: 10.1016/0165-1218(79)90026-0.

Abstract

12 permitted food colours in use were screened for geno-toxicity. Mitotic gene conversion in Saccharomyces cerevisiae was used as the end-point. Each food colour was tested in stationary-phase as well as log-phase cells but without microsomal activation. These food colours did not cause any increase in mitotic gene conversion in diploid yeast BZ 34.

摘要

对12种允许使用的食用色素进行了基因毒性筛查。以酿酒酵母中的有丝分裂基因转换作为检测终点。每种食用色素在稳定期细胞和对数期细胞中进行了测试，但未进行微粒体活化。这些食用色素在二倍体酵母BZ 34中未导致有丝分裂基因转换增加。