泛发性脓疱型银屑病、急性泛发性发疹性脓疱病及其他脓疱反应：临床综述
Generalized Pustular Psoriasis, Acute Generalized Exanthematous Pustulosis, and Other Pustular Reactions: A Clinical Review.
作者信息
Gössinger Elisabeth, Dodiuk-Gad Roni, Mühleisen Beda, Oon Hazel H, Oh Choon Chiat, Maul Julia-Tatjana, Navarini Alexander A
机构信息
Department of Dermatology, University Hospital of Basel, Burgfelderstrasse 101, Basel 4055, Switzerland.
Department of Dermatology, Emek Medical Center, Bruce Rappaport Faculty of Medicine, Technion Institute of Technology, Haifa, 3525433 Israel; Division of Dermatology, Department of Medicine, University of Toronto, Toronto, Ontario M5S 1A1, Canada.
出版信息
Dermatol Clin. 2024 Apr;42(2):317-328. doi: 10.1016/j.det.2024.01.001.
Generalized pustular rashes have various etiologies and can be challenging to diagnose and manage at first presentation. The authors provide an in-depth analysis of common pustular skin eruptions including generalized pustular psoriasis (GPP) and acute generalized exanthematous pustulosis, focusing on their pathophysiology, triggers, clinical presentation, diagnostic challenges, and management strategies. The article also highlights recent advances in genetic research and biologic therapies for GPP and the future directions in personalized medicine and prevention strategies.
泛发性脓疱性皮疹有多种病因，在初次就诊时诊断和处理可能具有挑战性。作者对常见的脓疱性皮肤疹进行了深入分析，包括泛发性脓疱型银屑病（GPP）和急性泛发性发疹性脓疱病，重点关注其病理生理学、诱发因素、临床表现、诊断挑战及管理策略。本文还强调了GPP基因研究和生物治疗的最新进展以及个性化医学和预防策略的未来方向。
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