Cytogenetic studies in patients treated with penicillamine.
作者信息
Jensen M K, Rasmussen G G, Ingeberg S
出版信息
Mutat Res. 1979 Aug;67(4):357-9. doi: 10.1016/0165-1218(79)90032-6.
PMID:384237
Abstract
Cytogenetic studies were performed on bone-marrow cells from 11 patients with rheumatoid arthritis treated with penicillamine. One of the patients was studied while developing a granulocytopenia and thrombocytopenia. The findings show that penicillamine had no chromosome-damaging effect as estimated by the micronucleus test and by the number of structural chromosomal aberrations.
摘要
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