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肾上腺意外瘤:1例罕见的结外B细胞淋巴瘤病例

Adrenal Gland Incidentaloma: A Rare Case of Extranodal B-cell Lymphoma.

作者信息

Figueiredo Inês, Guimarães Francisco, Duarte Cristina, Fontes Luísa

机构信息

Department of Internal Medicine, Hospital Companhia União Fabril (CUF) Descobertas, Lisboa, PRT.

出版信息

Cureus. 2024 Jan 30;16(1):e53231. doi: 10.7759/cureus.53231. eCollection 2024 Jan.

DOI:10.7759/cureus.53231
PMID:38425629
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10902736/
Abstract

The prevalence of adrenal incidentalomas (i.e., incidental findings) has grown in recent years with the evolution of imaging methods. Adrenal masses can be benign or malignant. Malignant ones are less frequent, but the detection of primary adrenal neoplasms is even less frequent, especially in the case of a diffuse large B-cell lymphoma (DLBCL). This case concerns a 68-year-old man who presented to the emergency department due to fatigue and anorexia. Given his blood test results on admission, he underwent a computed tomography (CT) with angiography that identified a mass in the left adrenal gland with displacement of the ipsilateral kidney. Left tumorectomy, adrenalectomy, and nephrectomy were performed, and the mass corresponded to a nongerminal center-type DLBCL. This case highlights the importance of prompt diagnosis and surgical and pharmacologic treatment of DLBCL.

摘要

近年来,随着成像方法的发展,肾上腺偶发瘤(即偶然发现的病变)的患病率有所上升。肾上腺肿块可以是良性的,也可以是恶性的。恶性肿块较为少见,但原发性肾上腺肿瘤的检出更为罕见,尤其是在弥漫性大B细胞淋巴瘤(DLBCL)的情况下。本病例涉及一名68岁男性,因疲劳和厌食症就诊于急诊科。根据其入院时的血液检查结果,他接受了计算机断层扫描(CT)血管造影,发现左肾上腺有一个肿块,同侧肾脏移位。进行了左肿瘤切除术、肾上腺切除术和肾切除术,肿块为非生发中心型DLBCL。本病例强调了DLBCL及时诊断以及手术和药物治疗的重要性。

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本文引用的文献

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Clinical Features of 50 Patients With Primary Adrenal Lymphoma.50 例原发性肾上腺淋巴瘤患者的临床特征。
Front Endocrinol (Lausanne). 2020 Sep 24;11:595. doi: 10.3389/fendo.2020.00595. eCollection 2020.
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Primary adrenal lymphoma: a case of hiccups.原发性肾上腺淋巴瘤:一例呃逆病例
Oxf Med Case Reports. 2020 May 23;2020(4):omaa030. doi: 10.1093/omcr/omaa030. eCollection 2020 Apr.
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Clinical characteristics and outcomes of primary adrenal diffuse large B cell lymphoma in a large contemporary cohort: a SEER-based analysis.
在一个大型当代队列中,原发性肾上腺弥漫性大 B 细胞淋巴瘤的临床特征和结局:一项基于 SEER 的分析。
Ann Hematol. 2019 Sep;98(9):2111-2119. doi: 10.1007/s00277-019-03740-9. Epub 2019 Jun 21.
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THE EVALUATION OF INCIDENTALLY DISCOVERED ADRENAL MASSES.偶然发现的肾上腺肿块的评估。
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Immune evasion-related extranodal large B-cell lymphoma: A report of six patients with neoplastic PD-L1-positive extranodal diffuse large B-cell lymphoma.免疫逃逸相关结外大B细胞淋巴瘤:6例肿瘤性PD-L1阳性结外弥漫性大B细胞淋巴瘤患者的报告
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Curr Treat Options Oncol. 2018 Jun 21;19(8):38. doi: 10.1007/s11864-018-0555-8.
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Bilateral primary adrenal diffuse large B cell lymphoma without adrenal insufficiency: A case report and review of the literature.双侧原发性肾上腺弥漫性大B细胞淋巴瘤且无肾上腺功能不全:一例病例报告及文献复习
Mol Clin Oncol. 2017 Jul;7(1):145-147. doi: 10.3892/mco.2017.1264. Epub 2017 May 17.
8
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J Med Case Rep. 2017 Apr 15;11(1):108. doi: 10.1186/s13256-017-1271-x.
9
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Endocr Pract. 2015 Jul;21(7):719-24. doi: 10.4158/EP14471.OR. Epub 2015 Feb 25.
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