Department of Oral Pathology and Microbiology, Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research (SRIHER), Chennai, Tamil Nadu, India.
Department of Pediatric Dentistry, Centre for Early Childhood Caries Research (CECCRe), Sri Ramachandra Dental College and Hospital, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Am J Hum Biol. 2024 Aug;36(8):e24060. doi: 10.1002/ajhb.24060. Epub 2024 Mar 1.
Population-based variations have been reported in permanent teeth eruption but only sparse literature exists on the same. A systematic review and meta-analysis were performed to assess the global variations in eruption chronology of permanent teeth in children and adolescents and the role of sexes, jaws and classes of socio-economic status (SES) on timing of eruption was explored.
The protocol for the systematic review was registered in PROSPERO. An extensive search of PubMed, EMBASE, Google Scholar, EBSCO, Cochrane library, and anthropology databases was carried out until April 2023. Additionally, grey literature search and hand-searching of relevant key journals was done.
Overall, 3797 cross-sectional and longitudinal studies were retrieved from multiple databases. A total of 939, 191 participants were included from 80 studies of which, 41 were carried out in Asia, 26 in Europe, 5 in Africa, 4 in North America, and 4 in Oceania. The mandibular first molar eruption was found to be as early as 4.09 years while the maxillary second molar erupted as late as 13.45 years. Using a random effects model, 28 forest plots were generated. Meta-regression interpreted tooth eruption to be earlier in females and in the mandible.
The findings of this study show that the ages of permanent teeth eruption was advanced in the European population followed by Africa and Asia.
已有研究报道了恒牙萌出存在人群差异，但相关研究较少。本系统评价和荟萃分析旨在评估儿童和青少年恒牙萌出的时间变化，并探讨性别、颌骨和社会经济地位（SES）类别对萌出时间的影响。
本系统评价的方案已在 PROSPERO 中注册。我们对 PubMed、EMBASE、Google Scholar、EBSCO、Cochrane 图书馆和人类学数据库进行了广泛搜索，检索时间截至 2023 年 4 月。此外，还进行了灰色文献搜索和相关关键期刊的手工搜索。
我们从多个数据库共检索到 3797 项横断面和纵向研究。最终纳入了 80 项研究中的 939191 名参与者，其中 41 项研究在亚洲进行，26 项在欧洲进行，5 项在非洲进行，4 项在北美进行，4 项在大洋洲进行。下颌第一磨牙最早在 4.09 岁萌出，上颌第二磨牙最晚在 13.45 岁萌出。使用随机效应模型生成了 28 个森林图。元回归分析表明，女性和下颌的牙齿萌出时间更早。
本研究结果表明，欧洲人群的恒牙萌出年龄较早，其次是非洲和亚洲。
