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患者肺癌致脊神经根转移,酷似神经鞘瘤:病例报告及文献复习。

Sacral nerve root metastasis in a patient with lung carcinoma resembling neurinoma - a case report and literature review.

机构信息

Medical University of Plovdiv, Plovdiv, Bulgaria.

St George University Hospital, Plovdiv, Bulgaria.

出版信息

Folia Med (Plovdiv). 2024 Feb 29;66(1):136-141. doi: 10.3897/folmed.66.e111619.

Abstract

Intradural extramedullary metastases from systemic neoplasms are very rare, with an incidence ranging from 2% to 5% of all secondary spinal diseases. We present the case of a 53-year-old man diagnosed with lung adenocarcinoma with symptoms of severe back pain and tibial paresis. The magnetic resonance imaging (MRI) revealed an intradural lesion originating from the right S1 nerve root mimicking neurinoma. Total tumor removal was achieved via posterior midline approach. The histological examination was consistent with lung carcinoma metastasis. Due to the rarity of single nodular nerve root metastases, MRI images may be misinterpreted as nerve sheath tumors, such as schwannomas or neurofibromas. We performed a brief literature review outlining the mainstay of diagnosis, therapeutic approach, and the prognosis of these rare lesions.

摘要

椎管内髓外转移瘤来自全身肿瘤,非常罕见,占所有继发性脊柱疾病的 2%~5%。我们报告 1 例 53 岁男性,患有肺腺癌,表现为严重背痛和胫骨瘫痪。磁共振成像(MRI)显示起源于右侧 S1 神经根的硬脊膜内病变,类似于神经鞘瘤。通过后路正中入路实现了肿瘤的完全切除。组织学检查符合肺癌转移。由于单个结节性神经根转移非常罕见,MRI 图像可能被误诊为神经鞘肿瘤,如神经鞘瘤或神经纤维瘤。我们进行了简要的文献复习,概述了这些罕见病变的主要诊断、治疗方法和预后。

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