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脉搏血氧饱和度测定筛查先天性心脏病:系统评价。

Pulse oximetry test for screening congenital heart diseases: a systematic review.

机构信息

Universidade Federal do Paraná, Departamento de Enfermagem, Curitiba, PR, Brazil.

Instituto Joanna Briggs. São Paulo, SP, Brazil.

出版信息

Rev Esc Enferm USP. 2024 Mar 1;57:e20230215. doi: 10.1590/1980-220X-REEUSP-2023-0215en. eCollection 2024.

DOI:10.1590/1980-220X-REEUSP-2023-0215en
PMID:38426937
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10906467/
Abstract

OBJECTIVE

To determine the accuracy of the Pulse Oximetry Test (POT) in screening for Congenital Heart Diseases (CHD) in newborns in the first 48 hours of life.

METHOD

Systematic review of diagnostic test accuracy with meta-analysis. The selection of studies was carried out in June 2021. Studies were selected with newborns, in a hospital or home environment, without a previous diagnosis of CHD, regardless of gestational age at birth, who underwent POT within the first 48 hours after birth. Registration on the PROSPERO platform - CRD42021256286.

RESULTS

Twenty-nine studies were included, totaling a population of 388,491 newborns. POT demonstrated sensitivity of 47% (95% CI: 43% to 50%) and specificity of 98% (95% CI: 98% to 98%). Subgroup analyses were carried out according to the different testing period, inclusion of retests in protocols and population of premature newborns.

CONCLUSION

POT is a test with moderate sensitivity and high specificity. It is more effective when carried out within 24h - 48h of birth; in protocols that present retests, within two hours after the first measurement. It does not show satisfactory effectiveness for premature newborns.

摘要

目的

确定脉搏血氧仪测试(POT)在筛查新生儿生命最初 48 小时内先天性心脏病(CHD)的准确性。

方法

采用诊断测试准确性的系统评价和荟萃分析。研究选择于 2021 年 6 月进行。选择在医院或家庭环境中、无 CHD 先前诊断、无论出生时的胎龄如何、出生后 48 小时内接受 POT 的新生儿进行研究。在 PROSPERO 平台上进行注册 - CRD42021256286。

结果

共纳入 29 项研究,总计 388491 例新生儿。POT 显示出 47%(95%CI:43%至 50%)的敏感性和 98%(95%CI:98%至 98%)的特异性。根据不同的测试期、方案中是否包括复测以及早产儿人群进行了亚组分析。

结论

POT 是一种具有中等敏感性和高度特异性的测试。在出生后 24 小时至 48 小时内进行时效果更佳;在方案中进行复测时,在第一次测量后两小时内进行。它对早产儿的效果并不令人满意。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e3/10906467/d8ad80cba21e/1980-220X-reeusp-57-e20230215-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e3/10906467/610eba0d319b/1980-220X-reeusp-57-e20230215-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e3/10906467/df13f71f8e75/1980-220X-reeusp-57-e20230215-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e3/10906467/d8ad80cba21e/1980-220X-reeusp-57-e20230215-gf03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e3/10906467/610eba0d319b/1980-220X-reeusp-57-e20230215-gf01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e3/10906467/df13f71f8e75/1980-220X-reeusp-57-e20230215-gf02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7e3/10906467/d8ad80cba21e/1980-220X-reeusp-57-e20230215-gf03.jpg

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