亚急性硬化性全脑炎相关性肾小球病

Subacute sclerosing panencephalitis associated glomerulopathy.

作者信息

O'Regan S, Turgeon-Knaack E, Mongeau J G, Lapointe N, Nolin L, Robitaille P O

出版信息

Nephron. 1979;23(6):304-7. doi: 10.1159/000181655.

Abstract

Subacute sclerosing panencephalitis (SSPE) is a progressive neurologic disease associated with chronic measles infection. We have assessed renal function parameters and renal biopsy details in 14 patients with SSPE. All had normal renal function. However, 9 had microscopic hematuria. 9 patients had focal segmental mesangial proliferation and 5 had capillary wall thickening with deposits visible by light microscopy. 13 patients had glomerular C3 deposition and 4 had IgG deposits. SSPE is a disease caused by chronic viral infection, in which nephritogenic complex formation may occur.

摘要

亚急性硬化性全脑炎（SSPE）是一种与慢性麻疹感染相关的进行性神经疾病。我们评估了14例SSPE患者的肾功能参数及肾活检细节。所有患者肾功能均正常。然而，9例有镜下血尿。9例患者有局灶节段性系膜增生，5例有毛细血管壁增厚，光镜下可见沉积物。13例患者有肾小球C3沉积，4例有IgG沉积。SSPE是一种由慢性病毒感染引起的疾病，其中可能发生致肾炎复合物形成。