Bergmanson J P, Johnsson J, Söderberg P G, Philipson B T
Cornea. 1985;4(3):173-6.
The validity of using the aqueous humor lactate concentration as an indicator of corneal lactate production was tested. For this purpose, ten rabbits wore non-gas permeable contact lenses on one eye for 12 hours. Aqueous humor and corneal extracts were assayed for lactate by means of an enzymatic technique. The contact lens wear caused a limited increment in the corneal lactate concentration, but no change was recorded in the aqueous humor. We therefore conclude that the corneal lactate production has a negligible effect on the lactate concentration in aqueous humor. However, significant individual variations in lactate levels were recorded in the present study, as in earlier ones. Insufficient specificity in the currently used techniques for lactic acid concentration determination may in part explain this.
对将房水乳酸浓度用作角膜乳酸生成指标的有效性进行了测试。为此，十只兔子的一只眼睛佩戴非透气性隐形眼镜12小时。采用酶促技术测定房水和角膜提取物中的乳酸。佩戴隐形眼镜使角膜乳酸浓度有有限的增加，但房水中未记录到变化。因此我们得出结论，角膜乳酸生成对房水中的乳酸浓度影响可忽略不计。然而，本研究中记录到乳酸水平存在显著的个体差异，早期研究也是如此。目前用于测定乳酸浓度的技术特异性不足可能部分解释了这一点。
