Nordic Payers and Evidence, Coloplast Danmark A/S, Humlebæk, Denmark.
VIVE Health, Copenhagen, Denmark.
Expert Rev Pharmacoecon Outcomes Res. 2024 Apr;24(4):567-575. doi: 10.1080/14737167.2024.2324047. Epub 2024 Mar 7.
Living with an ostomy is often associated with costly complications. This study examined the burden of illness the first two years after ostomy creation.
Data from Danish national registries included all adult Danes with an ostomy created between 2002 and 2014.
Four cohorts consisted, respectively, of 11,385 subjects with a colostomy and 4,574 with an ileostomy, of which 1,663 subjects had inflammatory bowel disease (IBD) and 1,270 colorectal cancer as cause of their ileostomy. The healthcare cost was significantly higher for cases versus matched controls for all cohorts. In the first year, the total healthcare cost per person-year was €27,962 versus €4,200 for subjects with colostomy, €29,392 versus €3,308 for subjects with ileostomy, €15,947 versus €2,216 when IBD was the underlying cause, and €32,438 versus €4,196 when it was colorectal cancer. Healthcare costs decreased in the second year but remained significantly higher than controls. Hospitalization and outpatient services were primary cost drivers, with ostomy-related complications comprising 8-16% of hospitalization expenses.
Compared to controls, subjects with an ostomy bear a significant health and financial burden attributable to ostomy-related complications, in addition to the underlying disease, emphasizing the importance of better ostomy care to enhance well-being and reduce economic strain.
肠造口术后常伴有昂贵的并发症，本研究旨在探讨造口术后两年内的疾病负担。
本研究数据来源于丹麦国家登记处，纳入了 2002 年至 2014 年间所有丹麦成年人的肠造口术数据。
本研究包含四个队列，分别有 11385 例结肠造口术和 4574 例回肠造口术患者，其中 1663 例患者患有炎症性肠病（IBD），1270 例患者因结直肠癌而行回肠造口术。与对照组相比，所有队列的病例组的医疗费用均显著增加。在第一年，人均年总医疗费用分别为 27962 欧元（结肠造口术）、4200 欧元（对照组）、29392 欧元（回肠造口术）、15947 欧元（IBD）和 32438 欧元（结直肠癌）。第二年的医疗费用虽有所下降，但仍显著高于对照组。住院和门诊服务是主要的成本驱动因素，造口相关并发症占住院费用的 8-16%。
与对照组相比，肠造口术患者除了基础疾病外，还因造口相关并发症而承受着显著的健康和经济负担，这强调了加强造口护理以提高生活质量和减轻经济压力的重要性。
