Suppr超能文献

腹主动脉瘤手术后的性功能障碍:现有知识和未来方向。

Sexual Dysfunction After Abdominal Aortic Aneurysm Surgical Repair: Current Knowledge and Future Directions.

机构信息

Department of Urology, University Hospital of Nice, Nice, France.

Department of Vascular Surgery, University Hospital of Nice, Nice, France; University of Côte d'Azur, CNRS, Inserm, IRCAN, France; Department of Vascular Surgery, Henri Mondor University Hospital, Créteil, France.

出版信息

Eur J Vasc Endovasc Surg. 2018 Feb;55(2):267-280. doi: 10.1016/j.ejvs.2017.11.028. Epub 2017 Dec 29.

Abstract

BACKGROUND

Abdominal aortic aneurysm (AAA) represents a major health concern and the curative treatment relies on surgical approaches including open and endovascular aortic repair (EVAR). While epidemiological studies have addressed the major outcomes including mortality and life threatening complications, the impact of surgical intervention on sexual function has been less well described. The aim of this review was to summarise current knowledge on the occurrence of sexual dysfunction in the context of AAA surgical repair and to explore whether surgical techniques could have differential impact.

METHODS

The MEDLINE database was searched in May 2017 and all studies related to sexual dysfunction assessment following AAA surgical repair were included. Given the heterogeneity of the definitions of sexual dysfunction and its assessment, a comprehensive literature review was performed rather than a meta-analysis.

RESULTS

The published literature search identified 29 studies including prospective, retrospective, and single centre and multicentre trials. The post-operative erectile dysfunction prevalence varied from 7.4% to 79% following open repair and from 4.7% to 82% following EVAR. The incidence of de novo erectile dysfunction was estimated, respectively, at 20%, 26.6%, and 83% after open repair and at 11% and 14.3% after EVAR. Erectile dysfunction rates varied from 5.3% to 8.2% in patients who had EVAR with unilateral hypogastric artery exclusion and from 5.1% to 46.6% in patients who had bilateral hypogastric artery exclusion. The rates of retrograde ejaculation after surgery varied from 3.3% to 9% after open repair and from 6% to 6.6% after laparoscopic repair.

CONCLUSION

Clinical studies demonstrated heterogeneous results, which could be attributed mainly to methodology including study design and criteria used to evaluate sexual dysfunction. Given the potential consequences of sexual dysfunction on quality of life, this review highlights the real need to inform patients and to better assess this potential side effect to improve its management in patients undergoing AAA surgical repair.

摘要

背景

腹主动脉瘤(AAA)是一个主要的健康问题,其治疗方法主要依赖于手术治疗,包括开放手术和血管内修复(EVAR)。虽然流行病学研究已经涉及包括死亡率和危及生命的并发症在内的主要结果,但手术干预对性功能的影响却描述得不够充分。本综述的目的是总结目前关于 AAA 手术修复后性功能障碍发生的知识,并探讨手术技术是否会产生不同的影响。

方法

2017 年 5 月,我们在 MEDLINE 数据库中进行了检索,纳入了所有与 AAA 手术后性功能障碍评估相关的研究。由于性功能障碍的定义及其评估存在异质性,我们进行了全面的文献综述,而不是荟萃分析。

结果

已发表的文献检索确定了 29 项研究,包括前瞻性、回顾性、单中心和多中心试验。开放修复术后勃起功能障碍的患病率从 7.4%到 79%不等,EVAR 后从 4.7%到 82%不等。分别估计开放修复术后新发勃起功能障碍的发生率为 20%、26.6%和 83%,EVAR 后为 11%和 14.3%。在接受单侧髂内动脉结扎的 EVAR 患者中,勃起功能障碍发生率为 5.3%至 8.2%,在接受双侧髂内动脉结扎的患者中,勃起功能障碍发生率为 5.1%至 46.6%。手术后逆行射精的发生率在开放修复术后从 3.3%到 9%不等,在腹腔镜修复术后从 6%到 6.6%不等。

结论

临床研究结果存在差异,这主要归因于研究设计和用于评估性功能障碍的标准等方法学因素。鉴于性功能障碍对生活质量的潜在影响,本综述强调了告知患者并更好地评估这一潜在副作用的真正需要,以改善接受 AAA 手术修复的患者的管理。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验