Hashmi Sheikha Al, Hudar Shouq Al, Stephen Edwin, Riyami Dawood Al, Maawali Hanan Al, Abdelhady Ibrahim, Wahaibi Khalifa Al, Rizvi Syed
Sultan Qaboos University, Muscat, Oman.
Department of Surgery, Sultan Qaboos University, Muscat, Oman.
Sultan Qaboos Univ Med J. 2024 Feb;24(1):37-43. doi: 10.18295/squmj.9.2023.050. Epub 2024 Feb 28.
This study aimed to determine the risk factors associated with the failure of arteriovenous fistulae (AVF) maturation.
This retrospective cohort study was conducted from January 2014 to December 2018 in Sultan Qaboos University Hospital, Muscat, Oman. Patients were followed-up 3 months after surgery, and their electronic medical records were accessed for demographic and clinical data. Univariate analysis was used to determine the risk factors associated with early AVF maturation and multivariant analysis was used to determine the predictive factors for AVF failure.
A total of 269 patients were included. Female gender was a significant factor affecting AVF maturity ( = 0.049), while age ( = 0.626), diabetes ( = 0.954), hypertension ( = 0.378), dyslipidaemia ( = 0.907), coronary artery disease ( = 0.576), cerebrovascular accident ( = 0.864), congestive heart failure ( = 0.685), previous central venous catheterisation ( = 0.05), fistula type ( = 0.863) and fistula site ( = 0.861) did not affect AVF maturation. Binary logistic regression showed that all the risk factors were insignificant. Failure of early AVF maturation affected 11.5% in the cohort.
This study found that the proportion of early AVF maturation at our hospital is at par with that in the international literature. Failure of AVF maturation was significantly associated with the female gender. These findings can help nephrologists and vascular surgeons prognosticate AVF maturation rates. However, a larger study is needed for definitive conclusions.
本研究旨在确定与动静脉内瘘(AVF)成熟失败相关的危险因素。
本回顾性队列研究于2014年1月至2018年12月在阿曼马斯喀特的苏丹卡布斯大学医院进行。患者在手术后3个月进行随访,并查阅其电子病历以获取人口统计学和临床数据。单因素分析用于确定与早期AVF成熟相关的危险因素,多因素分析用于确定AVF失败的预测因素。
共纳入269例患者。女性是影响AVF成熟的一个重要因素(P = 0.049),而年龄(P = 0.626)、糖尿病(P = 0.954)、高血压(P = 0.378)、血脂异常(P = 0.907)、冠状动脉疾病(P = 0.576)、脑血管意外(P = 0.864)、充血性心力衰竭(P = 0.685)、既往中心静脉置管史(P = 0.05)、内瘘类型(P = 0.863)和内瘘部位(P = 0.861)均不影响AVF成熟。二元逻辑回归显示所有危险因素均无统计学意义。该队列中早期AVF成熟失败的发生率为11.5%。
本研究发现我院早期AVF成熟的比例与国际文献相当。AVF成熟失败与女性性别显著相关。这些发现有助于肾病学家和血管外科医生预测AVF的成熟率。然而,需要更大规模的研究才能得出确定性结论。