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病例报告:多处动脉粥样硬化斑块同时处于极端状态。

Case Report: Multiple atherosclerotic plaques at its extreme in synchrony.

作者信息

Toshniwal Saket, Sahai Isha, Ghosh Benumadhab, Chaturvedi Anuj, Agrawal Gajendra, Acharya Sourya, Kumar Sunil, Khadse Satish, Khurana Kashish

机构信息

General Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of higher education and research, Wardha, Maharashtra, 442001, India.

Cardiology, Jawaharlal Nehru medical college, Datta Meghe Institute of Higher Education and Research, Wardha, Maharashtra, 442001, India.

出版信息

F1000Res. 2024 Jan 24;12:738. doi: 10.12688/f1000research.135416.3. eCollection 2023.

Abstract

Peripheral artery (PAD) disease in association with renal artery stenosis is an important association which predicts the severity of the disease. An increase in the number of vessels affected by peripheral artery disease increases the chances of renal artery stenosis. In our case, the patient had primarily presented with anginal chest pain with complaints of claudication which on further investigation was diagnosed to be a triple vessel coronary artery disease along with bilateral subclavian and bilateral renal stenosis. On detailed history taking, risk factors like hypertension and chronic smoking was found to be present in our case which predisposed to peripheral artery disease secondary to atherosclerosis which was diagnosed on further investigations. Although the association of renal artery stenosis is not very rare in cases of severe peripheral vascular diseases, the presence of a triple vessel coronary artery disease in synchrony is what makes it unique. Take away lesson from this case report is importance of early diagnosis of dyslipidemia causing atherosclerosis and its complications. Multiple atherosclerotic lesions in synchrony i.e, bilateral renal artery stenosis with bilateral subclavian artery stenosis with coronary artery triple vessel atherosclerotic disease like in our case and its severity should create awareness among health care individuals and early treatment measures including lifestyle modifications should be considered to avoid such drastic events.

摘要

外周动脉疾病(PAD)合并肾动脉狭窄是一种重要的关联,可预测疾病的严重程度。外周动脉疾病受累血管数量的增加会增加肾动脉狭窄的几率。在我们的病例中,患者最初表现为心绞痛伴间歇性跛行,进一步检查诊断为三支血管冠状动脉疾病以及双侧锁骨下动脉和双侧肾动脉狭窄。在详细询问病史时,发现我们的病例存在高血压和长期吸烟等危险因素,这些因素易导致继发于动脉粥样硬化的外周动脉疾病,进一步检查得以确诊。虽然在严重外周血管疾病病例中肾动脉狭窄的关联并不十分罕见,但同时存在三支血管冠状动脉疾病使其具有独特性。从此病例报告中吸取的教训是早期诊断导致动脉粥样硬化及其并发症的血脂异常的重要性。像我们病例中同时出现的多个动脉粥样硬化病变,即双侧肾动脉狭窄、双侧锁骨下动脉狭窄以及冠状动脉三支血管动脉粥样硬化疾病及其严重程度,应引起医护人员的重视,应考虑采取包括生活方式改变在内的早期治疗措施以避免此类严重事件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/40bf/10905214/d80336a272ff/f1000research-12-161756-g0000.jpg

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