Wang Yue, Zheng Jingjing, Guo Zuofeng, Fang Xuejun
Ophthalmology, Liaoning Aier Eye Hospital, Shenyang, China.
AIER School of Ophthalmology, Central South University, Changsha, China.
Front Med (Lausanne). 2024 Feb 16;11:1320235. doi: 10.3389/fmed.2024.1320235. eCollection 2024.
To assess the efficacy and safety of intrastromal lenticule implantation for the treatment of hyperopia.
A systematic search of PubMed, Web of Science, Embase, Cochrane Library, China National Knowledge Internet, and Wan Fang Database identified studies on small-incision intrastromal lenticule implantation for hyperopia correction until January 2023. The Joanna Briggs Institute (JBI) critical appraisal tool was used to assess the quality of the retrospective research, and the Methodological Index for Non-randomized Studies (MINORS) was used to assess the quality of the prospective research. This study included postoperative visual outcomes, corneal morphology, and biomechanical outcomes.
A total of 456 articles were identified, of which 10 were included in the meta-analysis. Ten single-arm studies involving 190 eyes were included. A meta-analysis demonstrated that corneal intrastromal lenticule implantation treatment significantly improved hyperopia. Uncorrected distance visual acuity (UDVA) significantly improved compared to the preoperative value ( = 0.027), corrected distance visual acuity showed no difference compared to the preoperative value ( = 0.27), and 87% eyes have no loss of one or more lines in the Snellen lines of CDVA ( < 0.00001). There was a significant difference between the spherical equivalent refractive (SE) and preoperative examination ( < 0.00001), 52% of eyes had ±0.5 diopters (D) postoperative SE ( < 0.00001), and 74% eyes had ±1.0 D postoperative SE ( < 0.00001). The central corneal thickness (CCT) increased by 72.68 μm compared to that preoperatively ( < 0.00001), and corneal curvature increased by 4.18D ( < 0.00001). The -value decreased by 0.82 ( < 0.00001), and higher-order aberration (HOA) decreased by 0.66 ( < 0.00001).
Small-incision intrastromal lenticule implantation may be an effective solution for correcting hyperopia. The effect of improved vision is significant, but further exploration is needed for changes in corneal biomechanics and long-term safety.: https://www.crd.york.ac.uk/PROSPERO/, identifier: CRD42023432343.
评估基质内透镜植入术治疗远视的有效性和安全性。
通过对PubMed、Web of Science、Embase、Cochrane图书馆、中国知网和万方数据库进行系统检索，确定截至2023年1月关于小切口基质内透镜植入术矫正远视的研究。采用乔安娜·布里格斯研究所（JBI）的批判性评价工具评估回顾性研究的质量，采用非随机研究方法学指数（MINORS）评估前瞻性研究的质量。本研究包括术后视力结果、角膜形态和生物力学结果。
共识别出456篇文章，其中10篇纳入荟萃分析。纳入了10项涉及190只眼的单臂研究。荟萃分析表明，角膜基质内透镜植入术治疗可显著改善远视。与术前值相比，未矫正远视力（UDVA）显著改善（=0.027），矫正远视力与术前值相比无差异（=0.27），87%的眼在矫正远视力的斯内伦视力表中没有一行或多行视力下降（<0.00001）。等效球镜度（SE）与术前检查之间存在显著差异（<0.00001），52%的眼术后SE为±0.5屈光度（D）（<0.00001），74%的眼术后SE为±1.0 D（<0.00001）。中央角膜厚度（CCT）比术前增加了72.68μm（<0.00001），角膜曲率增加了4.18D（<0.00001）。 值下降了0.82（<0.00001），高阶像差（HOA）下降了0.66（<0.00001）。
小切口基质内透镜植入术可能是矫正远视的有效方法。视力改善效果显著，但角膜生物力学变化和长期安全性仍需进一步探索。：https://www.crd.york.ac.uk/PROSPERO/，标识符：CRD42023432343
