Challenges and Concerns in the Utilization of Meta-Analysis Software: Navigating the Landscape of Scientific Synthesis.

Meta-analysis has emerged as a pivotal tool for synthesizing evidence in scientific research, facilitated by the advent of meta-analysis software. While these tools have significantly streamlined the synthesis process, challenges and concerns persist, impacting the reliability and validity of meta-analytic findings. This editorial addresses key issues in the use of meta-analysis software, including heterogeneity, publication bias, data quality, model dependence, and user competence. As the scientific community increasingly relies on meta-analytic approaches, collaborative efforts are needed to establish standardized reporting guidelines, enhance data quality, and improve transparency. This study highlights the importance of addressing these challenges to ensure the continued evolution of meta-analysis as a robust and informative method for evidence synthesis in scientific research.