Gomes Dora, André Rui, Oliveira Catarina, Camões Sofia, Silva Catarina R, Mendes Miguel L
Internal Medicine, Centro Hospitalar Tondela-Viseu, Viseu, PRT.
Neurology, Centro Hospitalar Tondela-Viseu, Viseu, PRT.
Cureus. 2024 Jan 31;16(1):e53302. doi: 10.7759/cureus.53302. eCollection 2024 Jan.
The Epstein-Barr virus (EBV) is a DNA virus that has been infecting humans since ancient times, capable of causing a wide range of pathologies and affecting approximately 90% of the population. A 61-year-old male with no significant medical history presented with a 5-day history of imbalance and difficulty walking. Neurological examination revealed specific findings, including absent reflexes, bilateral asynergy, and gait abnormalities. Contrasting with Guillain-Barré Syndrome, lumbar puncture suggested a central nervous system infection. Serological testing confirmed Epstein-Barr virus (EBV) positivity, and intravenous immunoglobulin led to significant improvement. Electromyogram results suggested inflammatory/ipnfectious polyradiculopathy. Repeat EBV serology, showing strongly positive IgG and negative IgM, confirmed the diagnosis of Polyradiculoneuropathy secondary to EBV. This case underscores the rare neurological complications of EBV and the importance of considering viral infections in such presentations.
爱泼斯坦-巴尔病毒（EBV）是一种自古以来就一直感染人类的DNA病毒，能够引发多种病症，感染了大约90%的人口。一名61岁男性，无重大病史，出现了5天的平衡失调和行走困难症状。神经系统检查发现了特定体征，包括反射消失、双侧共济失调和步态异常。与吉兰-巴雷综合征不同，腰椎穿刺提示中枢神经系统感染。血清学检测证实爱泼斯坦-巴尔病毒（EBV）呈阳性，静脉注射免疫球蛋白后病情显著改善。肌电图结果提示炎症性/感染性多发性神经根病。重复EBV血清学检测显示IgG呈强阳性而IgM呈阴性，确诊为EBV继发的多发性神经根神经病。该病例强调了EBV罕见的神经系统并发症以及在此类病症中考虑病毒感染的重要性。
