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多指畸形与肱骨头半脱位:假性甲状旁腺功能减退症中的一种罕见体征。

Vara Deformity and Subluxed Humeral Heads: An Unusual Sign in Pseudohypoparathyroidism.

作者信息

Williams Mason A, Guruvadoo Kharina, Naffaa Lena

机构信息

Radiology, University of Central Florida College of Medicine, Orlando, USA.

Radiology, Nemours Children's Health System, Orlando, USA.

出版信息

Cureus. 2024 Jan 30;16(1):e53250. doi: 10.7759/cureus.53250. eCollection 2024 Jan.

Abstract

Pseudohypoparathyroidism is a rare disorder characterized by end-organ resistance to intact parathyroid hormone (PTH) and concomitant laboratory findings of hypocalcemia and hyperphosphatemia. Radiologic evidence of the disease may manifest as a variety of bone abnormalities. This case describes an 11-year-old female with a history of repaired bilateral slipped capital femoral epiphysis who presented with a limited range of motion of the bilateral upper extremities. Laboratory findings were consistent with pseudohypoparathyroidism. Radiographs revealed subchondral resorption of bilateral clavicular heads and multiple ribs and band lucencies of proximal humeral metaphyses, along with vara deformity and inferior subluxation of the humeral heads. This presentation adds to the spectrum of potential radiographic manifestations of pseudohypoparathyroidism.

摘要

假性甲状旁腺功能减退症是一种罕见的疾病,其特征为终末器官对完整甲状旁腺激素(PTH)抵抗,并伴有低钙血症和高磷血症的实验室检查结果。该疾病的放射学证据可能表现为多种骨骼异常。本病例描述了一名11岁女性,有双侧股骨头骨骺滑脱修复病史,出现双侧上肢活动范围受限。实验室检查结果与假性甲状旁腺功能减退症相符。X线片显示双侧锁骨头部、多根肋骨的软骨下吸收以及肱骨近端干骺端的多条带状透亮区,同时伴有肱骨头内翻畸形和下方半脱位。这一表现增加了假性甲状旁腺功能减退症潜在放射学表现的范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee1e/10905052/55c2638bbf80/cureus-0016-00000053250-i01.jpg

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