Somasundaram Karthikeyan R, Sankararaman Senthilkumar, Siddiqui Athar, Zadeh Hamid
Department of Orthopaedics, West Middlesex University Hospital Isleworth, TW7 6AF, United Kingdom.
Indian J Orthop. 2012 Nov;46(6):705-9. doi: 10.4103/0019-5413.104223.
Slipped capital femoral epiphysis (SCFE) is a disorder of adolescent age. Presentation of SCFE earlier than the expected age range should prompt the clinician to consider the presence of an underlying endocrinopathy. Early recognition and aggressive management of the predisposing endocrine disorder is crucial to prevent treatment failure and associated morbidity. We report the clinical presentation and treatment of an 8-year-old girl with bilateral slipped capital femoral epiphysis. The unusual age, persistent hypocalcemia, and associated distal femoral physeal deformities prompted further evaluations, which led to the diagnosis of pseudohypoparathyroidism type 1b. PHP type 1b is an extremely rare cause of SCFE and only a few cases have been reported. A delay in diagnosis in such case is not uncommon.
股骨头骨骺滑脱(SCFE)是一种青少年期疾病。SCFE出现在预期年龄范围之前应促使临床医生考虑潜在内分泌病的存在。对易患内分泌疾病进行早期识别和积极管理对于预防治疗失败及相关发病率至关重要。我们报告了一名8岁双侧股骨头骨骺滑脱女孩的临床表现及治疗情况。其异常的年龄、持续性低钙血症及相关的股骨远端骨骺畸形促使进一步评估,最终诊断为1b型假性甲状旁腺功能减退症。1b型PHP是SCFE极为罕见的病因,仅报道过少数病例。在此类病例中诊断延迟并不罕见。