Alqahtani Yahya S, Mahmoud Ashraf M, El-Wekil Mohamed M
Department of Pharmaceutical Chemistry, College of Pharmacy, Najran University, Najran, Saudi Arabia.
Department of Pharmaceutical Analytical Chemistry, Faculty of Pharmacy, Assiut University, Assiut, Egypt.
Anal Methods. 2024 Mar 22;16(12):1804-1810. doi: 10.1039/d3ay02288a.
In this study, we present a thoughtful integration of a dispersive solid-phase sorbent and oxine for the ultrasensitive and highly selective determination of Al ions. Cobalt ferrite nanoparticles (CoFeO NPs) modified with oxine were employed to facilitate the pre-concentration and estimation of Al, forming highly fluorescent chelate. The modification process included the assistance of sodium dodecyl sulfate (SDS) and sonication. The results indicated that the fluorescence intensity of Al-oxine/SDS@CoFeO NPs surpassed that of Al-oxine alone. The confirmation of the successful functionalization of CoFeO NPs with oxine was established through various techniques. Under optimal conditions, the fluorescence intensity exhibited a positive correlation with increasing concentrations of Al within the range of 0.029-600 ng mL, achieving a detection limit of 0.0087 ng mL based on signal to noise ratio 3 : 1. The developed method was effectively applied to the determination of Al in drinking water samples, yielding recoveries in the range of 97.19% to 103.13%, with a relative standard deviation (RSD%) not exceeding 3.78%.
在本研究中，我们提出了一种将分散固相吸附剂和8-羟基喹啉进行巧妙整合的方法，用于超灵敏且高选择性地测定铝离子。用8-羟基喹啉修饰的钴铁氧体纳米颗粒（CoFeO NPs）用于促进铝的预浓缩和测定，形成高荧光螯合物。修饰过程包括十二烷基硫酸钠（SDS）的辅助和超声处理。结果表明，Al-8-羟基喹啉/SDS@CoFeO NPs的荧光强度超过了单独的Al-8-羟基喹啉。通过各种技术证实了8-羟基喹啉对CoFeO NPs的成功功能化。在最佳条件下，荧光强度与0.029-600 ng mL范围内铝浓度的增加呈正相关，基于信噪比3:1实现了0.0087 ng mL的检测限。所开发的方法有效地应用于饮用水样品中铝的测定，回收率在97.19%至103.13%范围内，相对标准偏差（RSD%）不超过3.78%。
