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验证斯洛文尼亚版蒙特利尔认知评估量表作为轻度认知障碍筛查工具的有效性。

Validation of the Slovenian version of the Montreal Cognitive Assessment Scale as a screening tool for the detection of mild cognitive impairment.

机构信息

Department of Neurology, University Medical Center Ljubljana, Zaloška Cesta 2a, 1000, Ljubljana, Slovenia.

Medical Faculty, University of Ljubljana, Ljubljana, Slovenia.

出版信息

Acta Neurol Belg. 2024 Apr;124(2):543-547. doi: 10.1007/s13760-024-02487-z. Epub 2024 Mar 4.

Abstract

OBJECTIVE

The Montreal cognitive assessment scale (MoCA) is commonly used for detecting individuals with mild cognitive impairment (MCI). The aim of the present study was to evaluate the validity of the Slovenian MoCA as a screening tool for MCI and to determine the optimal cut-off point to detect MCI in the elderly population.

METHODS

Mini-Mental State Examination (MMSE), MoCA, and neuropsychological testing assessment were conducted on 93 individuals aged ≥ 60 years. MCI was found in 35 individuals with 58 cognitively asymptomatic controls. Cut-off values, sensitivity, and specificity of MoCA were calculated with the receiver operating characteristic curve.

RESULTS

MCI and healthy individuals did not differ with respect to age and education. Healthy individuals (M = 24.5, SD = 1.7) performed significantly better on MoCA compared to MCI individuals (M = 21.4, SD = 3.2) (p < 0.001). The Cronbach's α of MoCA as an index of internal consistency was 0.64. MoCA distinguished between healthy controls and MCI individuals with a sensitivity of 77% and specificity of 74%, using a cut-off of 23/24 points.

CONCLUSION

The Slovenian version of MoCA demonstrates an optimal cut-off value of 23/24 points for detecting older individuals with MCI. As a screening tool for MCI, its better diagnostic accuracy makes it preferable to using MMSE.

摘要

目的

蒙特利尔认知评估量表(MoCA)常用于检测轻度认知障碍(MCI)患者。本研究旨在评估斯洛文尼亚 MoCA 作为 MCI 筛查工具的有效性,并确定用于检测老年人群 MCI 的最佳截断值。

方法

对 93 名年龄≥60 岁的个体进行了简易精神状态检查(MMSE)、MoCA 和神经心理学测试评估。在 35 名 MCI 患者和 58 名认知无症状对照者中发现了 MCI。使用受试者工作特征曲线计算 MoCA 的截断值、敏感性和特异性。

结果

MCI 和健康个体在年龄和教育程度方面无差异。健康个体(M=24.5,SD=1.7)在 MoCA 上的表现明显优于 MCI 个体(M=21.4,SD=3.2)(p<0.001)。MoCA 的内部一致性 Cronbach's α 为 0.64。MoCA 区分了健康对照组和 MCI 个体,截断值为 23/24 点时,敏感性为 77%,特异性为 74%。

结论

斯洛文尼亚版 MoCA 显示出 23/24 分的最佳截断值,可用于检测患有 MCI 的老年人。作为 MCI 的筛查工具,其更高的诊断准确性使其优于 MMSE。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca4e/10965639/6f512bbec737/13760_2024_2487_Fig1_HTML.jpg

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