Department of Environmental Health Engineering, School of Public Health, Social Determinants of Health Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
School of Medicine, Social Medicine Department, Social Determinants of Health Research Center, Gonabad University of Medical Sciences, Gonabad, Iran.
Environ Sci Pollut Res Int. 2024 Apr;31(16):24051-24063. doi: 10.1007/s11356-024-32654-x. Epub 2024 Mar 4.
Raisins and grape pekmez are consumed commonly by human all over the globe. Consumption of contaminated foods may be the likely pathway of heavy metal exposure. Therefore, the objectives of the present research were to quantify trace elements concentration in raisins and grape pekmez produced from locally grown grapes in Gonabad and to assess non-carcinogenic (HQ and HI) and carcinogenic (total cancer risk, CRt) health risks caused by trace elements exposure via oral intake of these products for children, teenagers, and adults. For this purpose, a totally 30 (15 raisins and 15 grape pekmez) samples were purchased from the vineyard gardeners and examined for ten trace elements including As, Cd, Co, Cr, Cu, Fe, Mn, Ni, Pb, and Zn. The HI values signaled that the studied population consuming these products is at risk. The HQ, HI, and CRt values of the elements were in order of children > teenagers > adults. The highest cancer risk contribution was attributed to As and Ni for all the studied age groups in both raisins and grape pekmez samples. However, it is recommended that the concentration of trace elements in the soil and crops of the study area and its related health risks be regularly monitored to avoid significant health risks in the future.
葡萄干和葡萄浓汁在全球范围内被人类广泛食用。食用受污染的食物可能是重金属暴露的可能途径。因此,本研究的目的是定量测定产自贡纳巴德本地种植的葡萄的葡萄干和葡萄浓汁中的微量元素浓度,并评估通过食用这些产品摄入微量元素对儿童、青少年和成年人造成的非致癌(HQ 和 HI)和致癌(总癌症风险,CRt)健康风险。为此,从葡萄园园丁那里购买了总共 30 个(15 个葡萄干和 15 个葡萄浓汁)样本,对包括砷、镉、钴、铬、铜、铁、锰、镍、铅和锌在内的十种微量元素进行了检测。危害指数值表明,食用这些产品的研究人群面临风险。对于所有研究的年龄组,元素的 HQ、HI 和 CRt 值均为儿童 > 青少年 > 成年人。在葡萄干和葡萄浓汁样本中,砷和镍对所有研究年龄组的癌症风险贡献最大。然而,建议定期监测研究区域土壤和作物中的微量元素浓度及其相关健康风险,以避免未来出现重大健康风险。