• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

应激大鼠释放的气味会使非应激大鼠产生阿片类镇痛作用。

Odors released by stressed rats produce opioid analgesia in unstressed rats.

作者信息

Fanselow M S

出版信息

Behav Neurosci. 1985 Jun;99(3):589-92. doi: 10.1037//0735-7044.99.3.589.

DOI:10.1037//0735-7044.99.3.589
PMID:3843728
Abstract

When unstressed rats were placed in a chamber containing the odor of a conspecific that had received electric shock, they became analgesic as assessed by the formalin test. The odors of nonstressed conspecifics and novel odors produced no such effect. This analgesia was reversed by naltrexone. The data suggest that naturalistic stimuli innately associated with aversive environmental events can activate endogenous pain control mechanisms.

摘要

当将未受应激的大鼠置于含有曾遭受电击的同种个体气味的实验箱中时,通过福尔马林试验评估发现它们产生了镇痛作用。未受应激的同种个体的气味以及新的气味则不会产生这种效果。这种镇痛作用可被纳曲酮逆转。这些数据表明,与厌恶环境事件天生相关的自然主义刺激能够激活内源性疼痛控制机制。

相似文献

1
Odors released by stressed rats produce opioid analgesia in unstressed rats.应激大鼠释放的气味会使非应激大鼠产生阿片类镇痛作用。
Behav Neurosci. 1985 Jun;99(3):589-92. doi: 10.1037//0735-7044.99.3.589.
2
Effects of stress and beta-funal trexamine pretreatment on morphine analgesia and opioid binding in rats.
Life Sci. 1987 Dec 28;41(26):2835-44. doi: 10.1016/0024-3205(87)90430-9.
3
Chronic opioid antagonist treatment facilitates nonopioid, stress-induced analgesia.
Pharmacol Biochem Behav. 1987 Jul;27(3):525-7. doi: 10.1016/0091-3057(87)90359-5.
4
Opioid and non-opioid stress analgesia from cold water swim: importance of stress severity.冷水游泳产生的阿片类和非阿片类应激镇痛:应激严重程度的重要性。
Brain Res. 1986 Apr 30;372(1):167-71. doi: 10.1016/0006-8993(86)91472-1.
5
Naltrexone antagonizes the biobehavioral adaptation to cold water stress in rats.纳曲酮可拮抗大鼠对冷水应激的生物行为适应性。
Pharmacol Biochem Behav. 1985 May;22(5):769-79. doi: 10.1016/0091-3057(85)90526-x.
6
Species-specific danger signals, endogenous opioid analgesia, and defensive behavior.物种特异性危险信号、内源性阿片类镇痛与防御行为。
J Exp Psychol Anim Behav Process. 1986 Jul;12(3):301-9.
7
Discrimination of the odor of stressed rats.应激大鼠气味的辨别
Science. 1968 Aug 9;161(3841):599-601. doi: 10.1126/science.161.3841.599.
8
Involvement of central muscarinic cholinergic mechanisms in opioid stress analgesia.
Brain Res. 1983 Jul 4;270(2):289-93. doi: 10.1016/0006-8993(83)90603-0.
9
Quaternary naltrexone reveals the central mediation of conditional opioid analgesia.四氢纳曲酮揭示了条件性阿片类镇痛的中枢介导作用。
Pharmacol Biochem Behav. 1987 Jul;27(3):529-31. doi: 10.1016/0091-3057(87)90360-1.
10
Enhanced analgesic effects of stress following chronic administration of naltrexone in rats.长期给予大鼠纳曲酮后应激增强的镇痛作用。
Eur J Pharmacol. 1979 Oct 26;59(1-2):137-40. doi: 10.1016/0014-2999(79)90036-0.

引用本文的文献

1
Neuronal, affective, and sensory correlates of targeted helping behavior in male and female Sprague Dawley rats.雄性和雌性斯普拉格-道利大鼠中靶向帮助行为的神经元、情感和感觉相关性
Front Behav Neurosci. 2024 Apr 10;18:1384578. doi: 10.3389/fnbeh.2024.1384578. eCollection 2024.
2
CFA-treated mice induce hyperalgesia in healthy mice via an olfactory mechanism.CFA 处理过的小鼠通过嗅觉机制诱导健康小鼠产生痛觉过敏。
Eur J Pain. 2024 Apr;28(4):578-598. doi: 10.1002/ejp.2201. Epub 2023 Nov 20.
3
A Preliminary Investigation of Interspecific Chemosensory Communication of Emotions: Can Humans () Recognise Fear- and Non-Fear Body Odour from Horses ().
种间情绪化学感应通讯的初步研究:人类能否识别马的恐惧和非恐惧体臭?
Animals (Basel). 2021 Dec 8;11(12):3499. doi: 10.3390/ani11123499.
4
Innovations and advances in modelling and measuring pain in animals.动物模型和疼痛测量方面的创新与进展。
Nat Rev Neurosci. 2022 Feb;23(2):70-85. doi: 10.1038/s41583-021-00536-7. Epub 2021 Nov 26.
5
The characteristic response of domestic cats to plant iridoids allows them to gain chemical defense against mosquitoes.家猫对植物环烯醚萜类化合物的特征性反应使它们能够获得针对蚊子的化学防御能力。
Sci Adv. 2021 Jan 20;7(4). doi: 10.1126/sciadv.abd9135. Print 2021 Jan.
6
Halal slaughtering, welfare, and empathy in farm animals: a review.农场动物的清真屠宰、福利与同理心:综述
Trop Anim Health Prod. 2018 Dec;50(8):1733-1738. doi: 10.1007/s11250-018-1644-1. Epub 2018 Jun 25.
7
Anterior Cingulate Cortex Contributes to Alcohol Withdrawal- Induced and Socially Transferred Hyperalgesia.扣带前皮质参与酒精戒断诱导和社会传递性痛觉过敏。
eNeuro. 2017 Jul 25;4(4). doi: 10.1523/ENEURO.0087-17.2017. eCollection 2017 Jul-Aug.
8
C-type allatostatins mimic stress-related effects of alarm pheromone on honey bee learning and memory recall.C型咽侧体抑制素模拟报警信息素对蜜蜂学习和记忆回忆的应激相关效应。
PLoS One. 2017 Mar 21;12(3):e0174321. doi: 10.1371/journal.pone.0174321. eCollection 2017.
9
Social transfer of pain in mice.老鼠的痛觉转移。
Sci Adv. 2016 Oct 19;2(10):e1600855. doi: 10.1126/sciadv.1600855. eCollection 2016 Oct.
10
N-methyl-D-aspartate receptor agonism and antagonism within the amygdaloid central nucleus suppresses pain affect: differential contribution of the ventrolateral periaqueductal gray.杏仁中央核内 N-甲基-D-天冬氨酸受体激动和拮抗作用抑制疼痛情感:腹外侧导水管周围灰质的不同贡献。
J Pain. 2014 Dec;15(12):1305-18. doi: 10.1016/j.jpain.2014.09.007. Epub 2014 Sep 23.