Davies D C, Horn G, McCabe B J
Behav Neurosci. 1985 Aug;99(4):652-60. doi: 10.1037//0735-7044.99.4.652.
The effects of the noradrenergic neurotoxin DSP4 on imprinting in domestic chicks were investigated. Chicks received either DSP4 or distilled water and were trained 60 hr after hatching by exposing them to either a rotating red box or a stuffed jungle fowl. Noradrenaline concentration was determined in Wulst and medial and basal forebrain samples. The medial forebrain sample comprised mainly the intermediate part of the medial hyperstriatum ventrale, a region previously shown to be intimately involved in imprinting. The DSP4 treatment reduced forebrain noradrenaline levels by about 65%. DSP4 profoundly impaired imprinting in box-trained chicks but not in fowl-trained chicks. In box-trained chicks, the strength of imprinting was positively correlated with noradrenaline concentration in both medial and basal forebrain samples. It is suggested on the basis of these and previous studies that some of the neural structures and mechanisms involved in imprinting on the fowl differ from those involved in imprinting on the box.
研究了去甲肾上腺素能神经毒素DSP4对家鸡印记行为的影响。雏鸡分别接受DSP4或蒸馏水注射，并在孵化后60小时通过将它们暴露于旋转的红色盒子或填充的原鸡来进行训练。测定了中脑和内侧及基底前脑样本中的去甲肾上腺素浓度。内侧前脑样本主要包括腹侧内侧纹状体中间部分，该区域先前已被证明与印记行为密切相关。DSP4处理使前脑去甲肾上腺素水平降低了约65%。DSP4严重损害了在盒子训练的雏鸡的印记行为，但对原鸡训练的雏鸡没有影响。在盒子训练的雏鸡中，印记强度与内侧和基底前脑样本中的去甲肾上腺素浓度呈正相关。基于这些研究和先前的研究表明，参与对原鸡印记的一些神经结构和机制与参与对盒子印记的不同。
