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韩国需要手术治疗的先天性和婴儿期白内障的全国发病率。

Nationwide incidence of congenital and infantile cataract requiring surgery in Korea.

机构信息

Department of Ophthalmology, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.

Department of Ophthalmology, Inje University College of Medicine, Inje University Busan Paik Hospital, Busan, South Korea.

出版信息

Sci Rep. 2024 Mar 4;14(1):5251. doi: 10.1038/s41598-024-53339-y.

DOI:10.1038/s41598-024-53339-y
PMID:38438402
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10912700/
Abstract

Congenital and infantile (CI) cataract is one of the most important and preventable cause of blindness in children, but the incidence has not been studied in Korea. We collected data from the national claims database of the National Health Insurance Service of Korea from 2002 through 2019. We identified children who underwent cataract surgery within the age of 5 years, and cumulative incidence rates were calculated for each of the three age criteria. 989 patients out of 4,221,459 births underwent surgery with CI cataract during the period. The cumulative incidence rates per 10,000 births were 1.60 (0-1 years), 2.38 (0-3 years), and 2.95 (0-5 years), respectively. The incidence peaked in the 2007 birth cohort, which coincides with the start of the national screening program for infants/children. Primary intraocular lens implantation was performed in 439 patients (44%). Strabismus and glaucoma requiring surgery occurred in 291 patients (29.4%) and 32 patients (3.2%), respectively, within 8 years after cataract surgery. The incidence rates of CI cataract in Korea appear to be comparable to previous studies in other regions. The early screening program for infants may reduce delayed diagnosis and increase the proportion of patients undergoing surgery at a critical time for visual development.

摘要

先天性和婴儿期白内障是儿童失明的最重要和可预防原因之一,但在韩国尚未对此发病率进行研究。我们从韩国国家健康保险服务的国家索赔数据库中收集了 2002 年至 2019 年的数据。我们确定了在 5 岁以内接受白内障手术的儿童,并按三个年龄标准计算了累积发病率。在该期间,989 例患者(4221459 例出生中的 2.38%)接受了先天性白内障手术。每 10000 例出生的累积发病率分别为 1.60(0-1 岁)、2.38(0-3 岁)和 2.95(0-5 岁)。发病率在 2007 年出生队列中达到峰值,这与全国婴儿/儿童筛查计划的开始时间相吻合。在白内障手术后 8 年内,439 例患者(44%)进行了原发性眼内晶状体植入术。291 例患者(29.4%)和 32 例患者(3.2%)分别发生斜视和青光眼,需要手术治疗。韩国的先天性白内障发病率似乎与其他地区的先前研究相当。婴儿早期筛查计划可能会减少延迟诊断,并增加在视觉发育关键时期接受手术的患者比例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5834/10912700/e8b562026d27/41598_2024_53339_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5834/10912700/e8b562026d27/41598_2024_53339_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5834/10912700/e8b562026d27/41598_2024_53339_Fig1_HTML.jpg

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