School of Pharmacy, Alborz University of Medical Sciences, Karaj, Iran.
Department of Pharmacoeconomics and Pharma Management, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Obes Surg. 2024 May;34(5):1834-1845. doi: 10.1007/s11695-024-07104-9. Epub 2024 Mar 4.
This umbrella review amalgamates the outcomes of economic evaluations pertaining to bariatric surgeries, pharmacotherapy, and gastric balloon for adult obesity treatment. Six databases were systematically searched. The inclusion criteria were established following the Patient/population Intervention Comparison and Outcomes (PICO) statement. Fifteen reviews met all the inclusion criteria. Eight studies focused on surgical interventions, four on pharmacotherapy, and three on both interventions. No systematic review of the economic evaluation of gastric balloons was identified. The majority of reviews advocated bariatric surgery as a cost-effective approach; however, there was discordance in the interpretation of pharmacological cost-effectiveness. Most of the economic evaluations were conducted from the payer and the healthcare system perspectives. We propose that future economic evaluations assessing weight loss interventions in adults adopt a societal perspective and longer-term time horizons.
本伞状综述综合了有关成人肥胖治疗的减肥手术、药物治疗和胃气球的经济评估结果。系统地在六个数据库中进行了检索。纳入标准是根据患者/人群干预比较和结局（PICO）声明制定的。有 15 项综述符合所有纳入标准。8 项研究侧重于手术干预，4 项研究侧重于药物治疗，3 项研究同时涉及这两种干预措施。没有发现对胃气球经济评估的系统综述。大多数综述认为减肥手术是一种具有成本效益的方法；然而，在药物经济学成本效益的解释上存在分歧。大多数经济评估都是从付款人和医疗保健系统的角度进行的。我们建议，未来评估成人减肥干预措施的经济评估采用社会视角和更长的时间范围。
