Department of Gastrointestinal Surgery, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, People's Republic of China.
Updates Surg. 2024 Aug;76(4):1521-1527. doi: 10.1007/s13304-024-01781-y. Epub 2024 Mar 4.
With the emergence of novel variants, Omicron variant caused a different clinical picture than the previous variants and little evidence was reported regarding perioperative outcomes after Omicron variants. The aim of the study was to evaluate the postoperative outcomes of gastrointestinal cancer patients following Omicron variants infection and also to determine the timing of surgery after infection recovery. A total of 124 patients who underwent gastrointestinal cancer surgery with prior SARS-CoV-2 infection between December 2022 and February 2023 were retrospectively reviewed. 174 cases underwent the same operation during December 2018 and February 2019 as control group. SARS-CoV-2-infected patients were further categorized into three groups based on infected time (1-3 weeks; 4-6 weeks; and ≥ 7 weeks). 90.3% of SARS-CoV-2-infected patients had mild symptoms. The COVID-19 vaccination rate was 71.0%, with a full vaccination rate of 48.4%. There were no significant differences in 30-day morbidity and mortality. There was also no significant difference in pulmonary complications, cardiovascular complications, and surgical complications between the three different diagnosis time groups. In conclusion, reducing waiting time for elective surgery was safe for gastrointestinal cancer patients in the context of an increased transmissibility and milder illness severity with Omicron variant.
随着新型变异株的出现，奥密克戎变异株引起的临床症状与之前的变异株不同，关于奥密克戎变异株感染后围手术期结局的证据很少。本研究旨在评估奥密克戎变异株感染后接受胃肠道癌症手术患者的术后结局，并确定感染恢复后手术的时机。回顾性分析了 2022 年 12 月至 2023 年 2 月期间因 SARS-CoV-2 感染而接受胃肠道癌症手术的 124 例患者。将同期（2018 年 12 月和 2019 年 2 月）接受相同手术的 174 例患者作为对照组。根据感染时间（1-3 周、4-6 周和≥7 周）将 SARS-CoV-2 感染患者进一步分为三组。90.3%的 SARS-CoV-2 感染患者症状轻微。COVID-19 疫苗接种率为 71.0%，完全接种率为 48.4%。30 天发病率和死亡率无显著差异。三组不同诊断时间的患者之间肺部并发症、心血管并发症和手术并发症也无显著差异。结论：在奥密克戎变异株传染性增加且疾病严重程度较轻的情况下，减少择期手术的等待时间对胃肠道癌症患者是安全的。
