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[细菌性内源性眼内炎:病原体谱与药物治疗]

[Bacterial endogenous endophthalmitis : Spectrum of pathogens and drug therapy].

作者信息

Ness Thomas

机构信息

Klinik für Augenheilkunde, Universitätsklinikum Freiburg, Killianstr. 5, 79106, Freiburg, Deutschland.

Albert-Ludwigs Universität Freiburg, Medizinische Fakultät, Freiburg, Deutschland.

出版信息

Ophthalmologie. 2024 Apr;121(4):264-271. doi: 10.1007/s00347-024-01995-w. Epub 2024 Mar 4.

Abstract

Endogenous endophthalmitis represents an ophthalmological emergency requiring immediate diagnostics and treatment. Pathogens should be detected using appropriate methods, such as the Freiburg endophthalmitis set. In bacterial endophthalmitis both Gram-positive and Gram-negative bacteria can be detected. Frequent underlying sources include endocarditis, gastrointestinal or urogenital surgery, indwelling venous catheters, liver abscesses, skin or soft tissue infections, meningitis or less commonly, intravenous drug abuse. The treatment consists of systemic and intraocular administration of antibiotics and vitrectomy. Systemic or intraocular corticosteroids can additionally be considered.

摘要

内源性眼内炎是一种眼科急症,需要立即进行诊断和治疗。应使用适当的方法检测病原体,如弗莱堡眼内炎检测套装。在细菌性眼内炎中,革兰氏阳性菌和革兰氏阴性菌均可被检测到。常见的潜在感染源包括心内膜炎、胃肠道或泌尿生殖系统手术、留置静脉导管、肝脓肿、皮肤或软组织感染、脑膜炎,或较少见的静脉药物滥用。治疗包括全身及眼内应用抗生素和玻璃体切除术。此外,可考虑全身或眼内应用糖皮质激素。

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