Department of Spine Surgery and Department of Pediatrics, The Third Xiangya Hospital, Central South University, Changsha, Hunan, China.
Hum Vaccin Immunother. 2024 Dec 31;20(1):2321672. doi: 10.1080/21645515.2024.2321672. Epub 2024 Mar 4.
To prevent COVID-19, the COVID-19 vaccine has been widely administered worldwide, but various complications accompany this vaccine. The aim of this study was to investigate the demographic patterns, clinical features, diagnostic findings, and treatment outcomes associated with shoulder injury related to vaccine administration (SIRVA). This study examined 22 patients with SIRVA following COVID-19 vaccination from the Web of Science (WOS) and PubMed databases. The patients were categorized based on sex, age, type of COVID-19 vaccine received, dose administered, latency of symptom onset, and the presence of specific clinical manifestations. Patients, evenly distributed by sex (12 females, 10 males), and aged 21 to 84 years (mean age 46.6), were analyzed. SIRVA cases were reported across all age groups. The Pfizer - BioNTech COVID-19 vaccine had the highest incidence ( = 8), followed by the Oxford/AstraZeneca COVID-19 vaccine ( = 4). Symptoms, primarily shoulder pain ( = 22) and shoulder mobility disorders ( = 18), occurred within three days post-vaccination. Some patients also reported shoulder swelling ( = 5) and fever ( = 2). Imaging revealed nonspecific X-ray findings, supraspinatus tendon calcification ( = 2), and shoulder edema and inflammation on MRI ( = 12). This study provides insights into the clinical aspects of SIRVA related to COVID-19 vaccination. Recognition and appropriate management of these complications are crucial for optimal patient outcomes.
为预防 COVID-19,全球范围内广泛接种了 COVID-19 疫苗,但该疫苗伴随各种并发症。本研究旨在调查与疫苗接种相关的肩损伤(SIRVA)的人口统计学模式、临床特征、诊断发现和治疗结果。本研究从 Web of Science(WOS)和 PubMed 数据库中检查了 22 例 COVID-19 疫苗接种后出现 SIRVA 的患者。根据性别、年龄、接种的 COVID-19 疫苗类型、接种剂量、症状发作潜伏期以及特定临床表现,对患者进行了分类。患者按性别平均分配(12 名女性,10 名男性),年龄为 21 至 84 岁(平均年龄为 46.6 岁)。所有年龄段均报告了 SIRVA 病例。辉瑞-生物技术公司的 COVID-19 疫苗发病率最高( = 8),其次是牛津/阿斯利康 COVID-19 疫苗( = 4)。症状主要为肩部疼痛( = 22)和肩部运动障碍( = 18),发生在接种疫苗后三天内。一些患者还报告了肩部肿胀( = 5)和发热( = 2)。影像学显示 X 线无特异性发现、冈上肌腱钙化( = 2)和肩部水肿和炎症 MRI( = 12)。本研究提供了 COVID-19 疫苗接种相关 SIRVA 的临床方面的见解。认识和适当管理这些并发症对于获得最佳患者结果至关重要。