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需要住院治疗的儿童精神疾病患者中伴有和不伴有原发性精神病性障碍的精神病症状。

Psychotic symptoms with and without a primary psychotic disorder in children requiring inpatient mental health admission.

机构信息

South London and Maudsley NHS Foundation Trust, London, UK.

UCL Institute of Education, Department of Psychology & Human Development, London, UK.

出版信息

Eur Psychiatry. 2024 Mar 5;67(1):e25. doi: 10.1192/j.eurpsy.2024.23.

Abstract

Psychotic symptoms are relatively common in children and adolescents attending mental health services. On most occasions, their presence is not associated with a primary psychotic disorder, and their clinical significance remains understudied. No studies to date have evaluated the prevalence and clinical correlates of psychotic symptoms in children requiring inpatient mental health treatment. All children aged 6 to 12 years admitted to an inpatient children's unit over a 9-year period were included in this naturalistic study. Diagnosis at discharge, length of admission, functional impairment, and medication use were recorded. Children with psychotic symptoms without a childhood-onset schizophrenia spectrum disorder (COSS) were compared with children with COSS and children without psychotic symptoms using Chi-square and linear regressions. A total of 211 children were admitted during this period with 62.4% experiencing psychotic symptoms. The most common diagnosis in the sample was autism spectrum disorder (53.1%). Psychotic symptoms were not more prevalent in any diagnosis except for COSS (100%) and intellectual disability (81.8%). Psychotic symptoms were associated with longer admissions and antipsychotic medication use. The mean length of admission of children with psychotic symptoms without COSS seems to lie in between that of children without psychotic symptoms and that of children with COSS. We concluded that psychotic symptoms in children admitted to the hospital may be a marker of severity. Screening for such symptoms may have implications for treatment and could potentially contribute to identifying more effective targeted interventions and reducing overall morbidity.

摘要

精神病症状在接受心理健康服务的儿童和青少年中较为常见。大多数情况下,它们的出现与原发性精神病无关,其临床意义仍有待研究。迄今为止,尚无研究评估需要住院精神治疗的儿童中精神病症状的患病率和临床相关性。本自然研究纳入了过去 9 年中在住院儿童病房住院的所有 6 至 12 岁儿童。记录出院时的诊断、住院时间、功能障碍和药物使用情况。使用卡方检验和线性回归,将无儿童期起病的精神分裂症谱系障碍(COSS)的精神病症状儿童与 COSS 儿童和无精神病症状儿童进行比较。在此期间共有 211 名儿童入院,其中 62.4%有精神病症状。样本中最常见的诊断是自闭症谱系障碍(53.1%)。除 COSS(100%)和智力障碍(81.8%)外,其他诊断的精神病症状并不更常见。精神病症状与住院时间延长和使用抗精神病药物有关。无 COSS 的精神病症状儿童的平均住院时间似乎介于无精神病症状儿童和 COSS 儿童之间。我们的结论是,住院儿童的精神病症状可能是严重程度的标志。对这些症状进行筛查可能对治疗有影响,并可能有助于确定更有效的针对性干预措施,从而降低整体发病率。

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Psychological interventions in psychosis in children and adolescents: a systematic review.儿童和青少年精神病中的心理干预:系统评价。
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