Department of Orthopaedics, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Department of Orthopaedics, Xiangyang Central Hospital, Affiliated Hospital of Hubei University of Arts and Science, Xiangyang, People's Republic of China.
Sci Prog. 2024 Jan-Mar;107(1):368504231223037. doi: 10.1177/00368504231223037.
In the reconstruction of large complex cutaneous wounds, a myriad of mechanical devices has been designed to facilitate primary wound closure. However, there is a dearth of studies elucidating how best to achieve optimum use and efficiency of skin stretching (SS) when using the device for immediate primary closure of defects.
Skin defect wounds (7 × 7 cm) were prepared on the back of three Bama miniature pigs. A total of 15 cycles of SS (cycle loading) were subsequently performed on the skin edges of the wound by EASApprox® SS system. Then, the changes in equidistant points were recorded after each cycle. After the SS test, all wounds were sutured under low tension.
Skin elongation was observed at all equidistant points on the back wounds of three Bama miniature pigs. Up to an additional 1.10 to 3.75 cm of tissue was garnered. The maximum skin elongation was typically achieved within eight cycles of stretching and relaxation. Beyond this range, additional stretching cycles did not result in further skin extension.
There may be a close link between mobilization range and the times of acute cyclic stretching (cycle loading) during the process of primary wound closure. However, larger studies are required to further evaluate the accuracy and effectiveness.
在重建大型复杂皮肤创面时，设计了无数的机械装置以促进一期伤口闭合。然而，对于使用该装置进行即时一期缺损闭合时，如何最佳地实现皮肤拉伸（SS）的最佳使用和效率，缺乏相关研究。
在三头巴马小型猪的背部制备 7×7cm 的皮肤缺损创面。使用 EASApprox® SS 系统对创面皮肤边缘进行总共 15 个循环的 SS（循环加载）。然后，记录每个循环后的等距点的变化。SS 试验后，所有伤口均在低张力下缝合。
在三头巴马小型猪的背部创面的所有等距点均观察到皮肤伸长。最多可获得 1.10 至 3.75cm 的组织。最大皮肤伸长通常在 8 个拉伸和放松循环内达到。超出此范围，进一步的拉伸循环不会导致进一步的皮肤延伸。
在一期伤口闭合过程中，活动范围与急性循环拉伸（循环加载）的次数之间可能存在密切联系。然而，需要更大规模的研究来进一步评估其准确性和有效性。
