Mustafa Muhammad Saqlain, Shafique Muhammad Ashir, Zaidi Syeda Dua E Zehra, Qamber Amna, Rangwala Burhanuddin Sohail, Ahmed Aftab, Zaidi Syeda Mahrukh Fatima, Rangwala Hussain Sohail, Uddin Muhammad Musab Nafees, Ali Mirha, Siddiq Mohammad Arham, Haseeb Abdul
Department of Medicine, Jinnah Sindh Medical University, Karachi, Pakistan.
Department of Paediatrics, National Institute of Child Health, Karachi, Pakistan.
Front Pediatr. 2024 Feb 19;12:1353508. doi: 10.3389/fped.2024.1353508. eCollection 2024.
This study addresses the pervasive issue of heightened preoperative anxiety in healthcare, particularly among pediatric patients. Recognizing the various sources of anxiety, we explored both pharmacological and nonpharmacological interventions. Focusing on distraction techniques, including active and passive forms, our meta-analysis aimed to provide comprehensive insights into their impact on preoperative anxiety in pediatric patients.
Following the PRISMA and Cochrane guidelines, this meta-analysis and systematic review assessed the efficacy of pharmaceutical and distraction interventions in reducing pain and anxiety in pediatric surgery. This study was registered on PROSPERO (CRD42023449979).
This meta-analysis, comprising 45 studies, investigated pharmaceutical interventions and distraction tactics in pediatric surgery. Risk of bias assessment revealed undisclosed risks in performance and detection bias. Distraction interventions significantly reduced preoperative anxiety compared to control groups, with notable heterogeneity. Comparison with Midazolam favored distraction techniques. Subgroup analysis highlighted varied efficacies among distraction methods, with a notable reduction in anxiety levels. Sensitivity analysis indicated stable results. However, publication bias was observed, suggesting a potential reporting bias.
Our study confirms distraction techniques as safe and effective for reducing pediatric preoperative anxiety, offering a valuable alternative to pharmacological interventions.
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=449979, PROSPERO [CRD42023449979].
本研究探讨了医疗保健中普遍存在的术前焦虑加剧问题，尤其是在儿科患者中。认识到焦虑的各种来源后，我们探索了药物和非药物干预措施。本荟萃分析聚焦于包括主动和被动形式在内的分心技术，旨在全面洞察其对儿科患者术前焦虑的影响。
遵循PRISMA和Cochrane指南，本荟萃分析和系统评价评估了药物和分心干预措施在减轻小儿外科手术疼痛和焦虑方面的疗效。本研究已在PROSPERO（CRD42023449979）上注册。
本荟萃分析纳入了45项研究，调查了小儿外科手术中的药物干预措施和分心策略。偏倚风险评估显示在实施和检测偏倚方面存在未披露的风险。与对照组相比，分心干预措施显著降低了术前焦虑，存在显著异质性。与咪达唑仑相比，分心技术更具优势。亚组分析突出了不同分心方法之间的不同疗效，焦虑水平显著降低。敏感性分析表明结果稳定。然而，观察到存在发表偏倚，提示可能存在报告偏倚。
我们的研究证实分心技术对于减轻儿科术前焦虑是安全有效的，为药物干预提供了有价值的替代方案。
https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=449979，PROSPERO [CRD42023449979]
