Sayed-Ahmed Mohammed Mamdouh, Taher Mohamed Badie, Zaytoun Rehab Abdel Hafeez, Abdel Hady Aisha Fawzy
Clinical Genetics Department, Human Genetics and Genome Research Institute, National Research Centre, Cairo, Egypt.
Otolaryngology Department, Phoniatric Unit, Faculty of Medicine, Fayoum University, El Haram Street, Giza, 12511 Egypt.
Indian J Otolaryngol Head Neck Surg. 2024 Feb;76(1):97-102. doi: 10.1007/s12070-023-04090-9. Epub 2023 Aug 9.
Sleep is a major concern in Down syndrome children. Obstructive sleep apnea, delayed sleep onset, night-time and early awakenings have been reported contributing to the cognitive and behavioral outcomes. The aim is to evaluate sleep related difficulties in Down syndrome young children. A questionnaire of sleep related difficulties was translated and validated into Arabic language then was filled in by caregivers of 45 Down syndrome and 48 normal children. The questionnaire consisted of sections related to snoring, breathing difficulties, mouth breathing, upper respiratory tract infections, sleep position, restless sleep and frequent awakening, and daytime behavior. The results show highly significant differences between the total and subtotal questionnaire scores with higher scores in the control group. The questionnaire has a good reliability. Test-retest reliability of the questionnaire revealed a significant positive correlation in the total questionnaire and all the subitems except for the 7th subitem of the daytime behavior which showed no significant correlation. The questionnaire showed 100% sensitivity and 70.8% Specificity with at cut-off value of 8.5. The sleep related difficulties questionnaire has good psychometric properties and could detect significant sleep problems in Down syndrome children.
The online version contains supplementary material available at 10.1007/s12070-023-04090-9.
睡眠是唐氏综合征儿童的一个主要问题。据报道，阻塞性睡眠呼吸暂停、入睡延迟、夜间和早醒会影响认知和行为结果。目的是评估唐氏综合征幼儿与睡眠相关的困难。一份与睡眠相关困难的问卷被翻译成阿拉伯语并进行了验证，然后由45名唐氏综合征儿童和48名正常儿童的照顾者填写。问卷包括与打鼾、呼吸困难、口呼吸、上呼吸道感染、睡眠姿势、睡眠不安和频繁醒来以及白天行为相关的部分。结果显示，问卷总分和各部分得分在两组间存在高度显著差异，对照组得分更高。该问卷具有良好的信度。问卷的重测信度显示，问卷总分及除白天行为第7项外的所有子项目均呈显著正相关，白天行为第7项无显著相关性。问卷在截断值为8.5时显示出100%的敏感性和70.8%的特异性。与睡眠相关困难的问卷具有良好的心理测量学特性，能够检测出唐氏综合征儿童存在的显著睡眠问题。
在线版本包含可在10.1007/s12070-023-04090-9获取的补充材料。
